Results 41 to 50 of about 5,842 (196)

Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data

BMJ Open, 2020
Introduction The benefits and risks of low-dose hydrocortisone in patients with septic shock have been investigated in numerous randomised controlled trials and trial-level meta-analyses. Yet, the routine use of this treatment remains controversial.
Yaseen Arabi, Sylvie Chevret, Laurent Billot, Anthony Gordon, Didier Keh, Romain Pirracchio, Balasubramanian Venkatesh, Djillali Annane, Andre Waschka, Jeremy Cohen, Simon Finfer, Naomi Hammond, John Myburgh, Anthony Delaney, Pierre Edouard Bollaert, Josef Briegel, Ling Liu, G Umberto, Liliana Mirea, L Charles, Nejla Tilouche, Surat Tongyoo, Ruiqiang Zheng   +22 more
doaj   +1 more source

Expanding the clinical spectrum of autosomal‐recessive renal tubular dysgenesis: Two siblings with neonatal survival and review of the literature

Molecular Genetics & Genomic Medicine, 2022
Background Autosomal‐recessive renal tubular dysgenesis (AR‐RTD) is a rare genetic disorder caused by defects in the renin‐angiotensin system that manifests as fetal anuria leading to oligohydramnios and Potter sequence.
Krista M. Vincent, Afrah Alrajhi, Joanna Lazier, Brigitte Bonin, Sarah Lawrence, Gabrielle Weiler, Christine M. Armour   +6 more
doaj   +1 more source

Cerebral salt wasting following tuberculous meningoencephalitis in an infant

Annals of Indian Academy of Neurology, 2012
In patients with central nervous system disease, life-threatening hyponatremia can result from either the syndrome of inappropriate secretion of antidiuretic hormone or cerebral salt wasting.
Syed Ahmed Zaki, Vijay Lad, Preeti Shanbag   +2 more
doaj   +1 more source

Effects of fludrocortisone on sympathetic nerve activity in humans. [PDF]

Hypertension, 1994
Fludrocortisone reduces plasma norepinephrine in healthy humans, but forearm vascular and pressor responses to norepinephrine are potentiated. The effects of fludrocortisone on sympathetic nerve activity in healthy humans are not known. To investigate these effects we evaluated muscle sympathetic nerve activity, heart rate, and arterial pressure in 11 ...
D Kahn, R F Rea, Allyn L. Mark, Christine A. Sinkey, Erling A. Anderson, D Mion   +5 more
openaire   +3 more sources

Current Screening Strategies for the Diagnosis of Adrenal Insufficiency in Children

Pediatric Health, Medicine and Therapeutics, 2023
Sasigarn A Bowden Division of Endocrinology, Department of Pediatrics, Nationwide Children’s Hospital/The Ohio State University College of Medicine, Columbus, OH, USACorrespondence: Sasigarn A Bowden, Nationwide Children’s Hospital, Division of ...
Bowden SA
doaj  

Evaluation of the role of hydrocortisone either alone or combined with fludrocortisone in the outcome of septic shock in adults

Ain Shams Journal of Anesthesiology, 2022
Background Management of sepsis is a time critical procedure; the consequences of improperly managed sepsis and septic shock can cause multiple organ dysfunction and death.
Heba A. Labib, Ali I. Hassan, Ayman M. Kamaly, Sherif S. Wahba, Mona A. Ammar   +4 more
doaj   +1 more source

Co-existence of Congenital Adrenal Hyperplasia and Familial Hypokalemic Periodic Paralysis due to CYP21A2 and SCN4A Pathogenic Variants

JCRPE, 2021
Steroid 21-hydroxylase deficiency is the most common cause of congenital adrenal hyperplasia (CAH), usually due to biallelic variants in CYP21A2. Classical 21-hydroxylase deficiency is characterised by virilisation of the external genitalia in females ...
Tuğba Kontbay, İhsan Turan
doaj   +1 more source

Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost‐Effectiveness Perspective

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Patients require additional treatment when pituitary surgery for Cushing's disease is unsuccessful. Exciting innovations in pituitary surgery bring hope for achieving better outcomes. Quantifying the potential value of these innovations using early health economic modelling can provide guidance throughout their development.
Femke J. C. Jacobs, Tim M. Govers, Jurgen J. Fütterer, Annenienke van de Ven, Maroeska M. Rovers   +4 more
wiley   +1 more source

Fludrocortisone Therapy in Renal Transplant Recipients with Persistent Hyperkalemia

Case Reports in Transplantation, 2012
Hyperkalemia after kidney transplantation is a common electrolyte disturbance and the risk factors are multifactorial. Pharmacotherapeutic agents for chronic management of hyperkalemia in kidney transplant patients may be relatively contraindicated or ...
K. Marfo, D. Glicklich
doaj   +1 more source

Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium

Journal of Pharmacological Sciences, 2016
We aimed to evaluate mineralocorticoid receptor (MR) expression in rat bladder and the physiological role of the MR-epithelial sodium channel (ENaC) pathway in controlling bladder function in 10–12-week-old, male Sprague–Dawley rats.
Seiji Yamamoto, Yuji Hotta, Kotomi Maeda, Tomoya Kataoka, Yasuhiro Maeda, Takashi Hamakawa, Shoichi Sasaki, Takahiro Yasui, Kiyofumi Asai, Kazunori Kimura   +9 more
doaj   +1 more source