Results 51 to 60 of about 6,859 (188)

Fludrocortisone therapy for persistent hyperkalaemia

, 2017
Background: Type 4 renal tubular acidosis causes hyperkalaemia, for which diabetes and medications commonly used in this patient group are aetiological factors. Here we describe the novel use of fludrocortisone in this difficult condition.
M. E. J. Lean, Lean, M.E.J., J. R. Petrie, Petrie, J.R., S. J. H. Dobbin, G. A. McKay, Dobbin, S.J.H., McKay, G.A.   +7 more
core   +1 more source

Current Screening Strategies for the Diagnosis of Adrenal Insufficiency in Children

Pediatric Health, Medicine and Therapeutics, 2023
Sasigarn A Bowden Division of Endocrinology, Department of Pediatrics, Nationwide Children’s Hospital/The Ohio State University College of Medicine, Columbus, OH, USACorrespondence: Sasigarn A Bowden, Nationwide Children’s Hospital, Division of ...
Bowden SA
doaj  

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

, 2018
International audienceBackground - Septic shock is characterized by dysregulation of the host response to infection, with circulatory, cellular, and metabolic abnormalities.
Baudin, François, Slama, Michel, Bohé, Julien, Claire Charpentier, Eric Bellissant, Roland Amathieu, Schwebel, Carole, Mohamed Ali Benali, Alain Combes, Chimot, Loïc, Boulain, Thierry, Capellier, Gilles, Dhonneur, Gilles, Loïc Chimot, Souweine, Bertrand, Brun-Buisson, Christian, Leroy, Olivier, Renault, Alain, Mégarbane, Bruno, Thierry Boulain, François, Bruno, Carole Schwebel, Charpentier, Claire, Fabrice Cook, Misset, Benoît, Gwenhael Colin, Bertrand Souweine, Maxime, Virginie, Michel Slama, Quenot, Jean-Pierre, Forceville, Xavier, Martin, Claude, Shidasp Siami, François Baudin, Petitpas, Franck, Virginie Maxime, Benoît Misset, Cook, Fabrice, Julien Bohé, Ali Benali, Mohamed, Bruno Megarbane, Combes, Alain, Dargent, Auguste, Annane, Djillali, Timsit, Jean-François, Gilles Dhonneur, Auguste Dargent, Christian Brun-Buisson, Karim Asehnoune, Jean-François Timsit, Loriferne, Jean-François, Olivier Leroy, Hissem, Tarik, Siami, Shidasp, Constantin, Jean-Michel, Amathieu, Roland, Emmanuelle Mercier, Alain Cariou, Franck Petitpas, Asehnoune, Karim, Bellissant, Eric, Jean-Michel Constantin, Colin, Gwenhael, Jean-François Loriferne, Alain Renault, Gilles Capellier, Jean-Pierre Quenot, Tarik Hissem, Cariou, Alain, Mercier, Emmanuelle, Djillali Annane, Bruno François, Claude Martin, Xavier Forceville   +73 more
core   +1 more source

Role of hydrocortisone with fludrocortisone early in septic shock: a randomized controlled study

Alexandria Journal of Medicine
Introduction Sepsis causes organ dysfunction due to the body’s response to infection, with early management essential. Septic shock involves persistent low blood pressure despite treatment, affecting all organ systems. Corticosteroids and glucocorticoids
Emad H. Hamouda, Amr A. Elmorsy, Ola S. Eldardiry, Amr H. Dahroug   +3 more
doaj   +1 more source

Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium

Journal of Pharmacological Sciences, 2016
We aimed to evaluate mineralocorticoid receptor (MR) expression in rat bladder and the physiological role of the MR-epithelial sodium channel (ENaC) pathway in controlling bladder function in 10–12-week-old, male Sprague–Dawley rats.
Seiji Yamamoto, Yuji Hotta, Kotomi Maeda, Tomoya Kataoka, Yasuhiro Maeda, Takashi Hamakawa, Shoichi Sasaki, Takahiro Yasui, Kiyofumi Asai, Kazunori Kimura   +9 more
doaj   +1 more source

Evaluation of the role of hydrocortisone either alone or combined with fludrocortisone in the outcome of septic shock in adults

Ain Shams Journal of Anesthesiology, 2022
Background Management of sepsis is a time critical procedure; the consequences of improperly managed sepsis and septic shock can cause multiple organ dysfunction and death.
Heba A. Labib, Ali I. Hassan, Ayman M. Kamaly, Sherif S. Wahba, Mona A. Ammar   +4 more
doaj   +1 more source

Long‐term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow‐up of over 20 years

Journal of Internal Medicine, EarlyView.
Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily affects female patients. There are scarce data evaluating the long‐term outcomes in POTS. Objectives This study sought to evaluate the long‐term impacts of POTS over multiple decades in adult patients.
Kate M. Bourne, Alfredo Gamboa, Bonnie Black, Juliette Hall, Italo Biaggioni, Cyndya A. Shibao, André Diedrich, Amanda Peltier, Giris Jacob, Luis Okamoto, Robert S. Sheldon, Satish R. Raj   +11 more
wiley   +1 more source

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder, Suzanna E. L. Temple, Niall Jefferson, David Brown, Kasee Stratton‐Gadke, Madelene Rich, Steve Rose, Kim Blake   +7 more
wiley   +1 more source

Stereoselective Production of Fluorohydrins Biocatalyzed by an Alcohol Dehydrogenase From Pichia glucozyma

ChemCatChem, Volume 18, Issue 11, 15 June 2026.
Ketoreductase from Pichia glucozyma (KRED1‐Pglu) has been successfully employed for the stereoselective bioreduction of α‐halogenated ketones using the purified protein, or alternatively a lyophilized whole cell preparation overexpressed in E. coli. Better chemoselectivities were found with pure biocatalyst, obtaining a series of chiral fluorohydrins ...
Marina García‐Ramos, Iván Lavandera, Francesco Molinari, Martina Letizia Contente, Vicente Gotor‐Fernández   +4 more
wiley   +1 more source

A Rare Clinical Presentation of Variegate Porphyria

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
WGS redirected the diagnostic focus, underscoring the complex interplay between porphyria and a potential MYMK‐related neuromuscular phenotype. ABSTRACT Background Variegate porphyria is a rare heme biosynthesis disorder caused by pathogenic variants in the PPOX gene.
I. Viakhireva, A. Murtazina, A. Orlova, N. Makretskaya, S. Nikitin, M. Skoblov   +5 more
wiley   +1 more source