Results 71 to 80 of about 10,175 (227)
Sepsis Endotypes Defined by Lymphocyte Thresholds and Inflammation Inform Precision Immunomodulation
MedComm, Volume 7, Issue 1, January 2026.Sepsis outcomes are shaped by immune–inflammatory imbalance. Integrative profiling identified critical lymphocyte thresholds and defined endotypes linking immune depletion with inflammation. Patients with low inflammation but lymphocyte loss benefited from corticosteroids, while hyperinflammatory endotypes did not. These findings establish a clinically
Zhongyi Sun +5 more
wiley +1 more source
Brain Differences in the Prefrontal Cortex, Amygdala, and Hippocampus in Youth with Congenital Adrenal Hyperplasia [PDF]
, 2020 Context: Classical Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency results in hormone imbalances present both prenatally and postnatally that may impact the developing brain.
Azad, Anisa +5 more
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Absorption and tolerability of taste-masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency [PDF]
, 2017 Objectives: There is no licensed, dose-appropriate formulation of hydrocortisone for children with adrenal insufficiency (AI) and patients rely on compounded adult medication.
Barbhaiya +25 more
core +1 more source
Case Reports in Pediatrics, 2016 Cerebral salt wasting (CSW) syndrome is an important cause of hyponatremia in head injuries apart from syndrome of inappropriate antidiuretic hormone (SIADH). Proper diagnosis and differentiation between these two entities are necessary for management as
Nagendra Chaudhary +3 more
doaj +1 more source
Corticosteroid Administration to Prevent Complications of Anterior Cervical Spine Fusion: A Systematic Review. [PDF]
, 2018 Study Design: Systematic review. Objectives: Anterior cervical approach is associated with complications such as dysphagia and airway compromise. In this study, we aimed to systematically review the literature on the efficacy and safety of corticosteroid
Abedi, Aidin +5 more
core +1 more source
Clinical management of neurogenic orthostatic hypotension
Annals of Movement Disorders, 2019 Neurogenic orthostatic hypotension is a common disorder often seen in elderly patients affected with neurodegenerative disorders and peripheral neuropathies.
Malligurki Raghurama Rukmani +3 more
doaj +1 more source
A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]
, 2017 Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho +5 more
core +3 more sources
European Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin +16 more
wiley +1 more source
Journal of Arrhythmia, Volume 41, Issue 6, December 2025.In this single‐center retrospective cohort of 117 patients with reflex syncope treated with dual‐chamber pacemakers, 12.8% had syncope recurrence within 6 months. Female sex, higher prior syncope burden, and a larger systolic blood pressure differential identified a high‐risk subgroup requiring closer follow‐up and adjunctive measures.
Thai Duy Vo +5 more
wiley +1 more source
Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation [PDF]
, 2000 Background. In this report, we compare the long-term outcome of pediatric liver transplantation (LTx) patients maintained with tacrolimus-based and with cyclosporine (CsA)-based immunosuppressive therapy.
Fung, J +7 more
core +1 more source