Results 71 to 80 of about 8,621 (184)

Pseudo‐Hypoaldosteronism Type 2 due to New Variants of KLHL3 Gene Diagnosed in an Adult Woman With Very High Sensitivity to Hydrochlorothiazide

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT We report a case of pseudo‐hypoaldosteronism type 2 (PHA II) in a hypertensive 55‐year‐old woman who carried new variants of the KLHL3 gene. Hypersensitivity to hydrochlorothiazide was noted. Low dosages of hydrochlorothiazide were needed to restore potassium levels.
Massimo Giusti   +2 more
wiley   +1 more source

Safety and Efficacy of Fludrocortisone in the Treatment of Cerebral Salt Wasting in Patients With Tuberculous Meningitis: A Randomized Clinical Trial

open access: yesJAMA Neurology, 2018
Importance Tuberculous meningitis is associated with high frequency of cerebral salt wasting. There is a paucity of objective information regarding the best method of treatment of this condition.
U. Misra, J. Kalita, Mritunjai Kumar
semanticscholar   +1 more source

Hyperkalaemia secondary to suspected transient hyporeninaemic hypoaldosteronism in a dog (in a dog)

open access: yesVeterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 12‐year‐7‐month‐old, female, entire beagle dog was presented to a referral hospital in England for a 10‐day history of tachypnoea and lethargy. Angiostrongylus vasorum ELISA test was positive, and the patient was started on fenbendazole. One week later, it became lethargic, anorexic, polyuric and polydipsic, and it was diagnosed with an open
Maria Jose Marin Lucas, Francesca Venier
wiley   +1 more source

Corticotherapy for traumatic brain-injured Patients - The Corti-TC trial: study protocol for a randomized controlled trial

open access: yesTrials, 2011
Background Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one study, hydrocortisone for treatment
Asehnoune Karim   +3 more
doaj   +1 more source

Mechanisms Underlying Treatment‐Resistant Depression: Exploring Sex‐Based Biological Differences

open access: yesJournal of Neurochemistry, Volume 169, Issue 9, September 2025.
Treatment‐resistant depression (TRD) affects about 30% of people with major depressive disorder and presents significant clinical and biological challenges. This review consolidates current evidence on the complex causes of TRD, focusing on biological differences based on sex.
Francisco E. R. da Silva   +7 more
wiley   +1 more source

The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

open access: yesJournal of the Renin-Angiotensin-Aldosterone System, 2019
Introduction: AZD9977 is a novel mineralocorticoid receptor (MR) modulator, which in preclinical studies demonstrated organ protection without affecting aldosterone-regulated urinary electrolyte excretion.
K. Bamberg   +4 more
semanticscholar   +1 more source

Statistical Analysis Plan for the Fludrocortisone Dose Response Relationship in Septic Shock (FluDReSS) trial

open access: gold, 2023
Laurent Billot   +6 more
openalex   +2 more sources

A Bulking Agent May Lead to Adrenal Insufficiency Crisis: A Case Report [PDF]

open access: yesActa Medica Iranica, 2011
Adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations.
Seyed Hossein Samadanifard   +4 more
doaj   +2 more sources

Clinical role of CYP2C19 polymorphisms in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

open access: yesActa Chimica Slovenica, 2016
Extraadrenal enzymes such as CYP2C19 may participate in residual 21-hydroxylation of progesterone leading to milder phenotypes of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD). Among 94 21OHD patients 28 were homozygous or
Urh Grošelj   +5 more
doaj   +1 more source

Mineralocorticoid replacement during infancy for salt wasting congenital adrenal hyperplasia due to 21-hydroxylase deficiency

open access: yesClinics, 2013
OBJECTIVE: The protocols for glucocorticoid replacement in children with salt wasting 21-hydroxylase deficiency are well established; however, the current recommendation for mineralocorticoid replacement is general and suggests individualized dose ...
Larissa G. Gomes   +3 more
doaj  

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