Results 51 to 60 of about 8,172 (206)

Fatores relacionados à utilização de flumazenil em pacientes hospitalizados [Factors related to use of flumazenil in hospitalized patients]

Revista Enfermagem UERJ, 2015
Interações medicamentosas (IM) exacerbam o risco de eventos adversos graves relacionados ao uso de benzodi­azepínicos. Este estudo objetivou conhecer aspectos relacionados à utilização de flumazenil em pacientes hospitalizados.
Elisangela da Costa Lima-Dellamora, Valcieny de Souza Sandes, Rosany Bochner, Guacira Correa Mattos, Sônia Maria Cezar Góes   +4 more
doaj   +1 more source

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, Volume 121, Issue 6, Page 1541-1556, June 2026.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source

Neurotransmitter Systems Underlying Freezing of Gait (FOG) in Parkinson's Disease

European Journal of Neuroscience, Volume 63, Issue 12, June 2026.
Freezing of gait (FOG) in Parkinson's disease (PD) arises from dysfunction across multiple neurotransmitter systems within distributed locomotor networks. While dopaminergic deficits contribute to levodopa‐responsive FOG, nondopaminergic systems including cholinergic, noradrenergic, serotonergic, and glutamatergic/GABAergic pathways play key roles in ...
Minsub Cho, Jin Whan Cho, Dallah Yoo, Jinse Park, Do‐Young Kwon, Seong‐Beom Koh, Jeong‐Ho Park, Jinyoung Youn   +7 more
wiley   +1 more source

Anxiolytic and Memory Protective Effects of Withanolide D Isolated From Acnistus arborescens in Adult Zebrafish

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Withanolide D Exhibits Anxiolytic and Memory‐Protective Effects. ABSTRACT This study evaluated the anxiolytic and memory‐protective effects of withanolide D in adult zebrafish (Danio rerio). The compound was administered at doses of 4, 20, and 40 mg/kg and showed no signs of toxicity after 96 h of observation at any of the doses tested.
Cléia Rocha de Sousa Feitosa, Joilna Alves Da Silva, Jéssica Bezerra Maciel, Ivana Carneiro Romão, Thais Rocha Cavalcante, Francisco Anderson Nascimento Barros, Nicole de Abreu Bandeira, Emmanuel Silva Marinho, Jane Eire Silva Alencar De Menezes, Maria Kueirislene Amâncio Ferreira, Antonio Wlisses Da Silva, Márcia Machado Marinho, Matheus Nunes Da Rocha, Otília Deusdênia Loiola Pessoa, Pedro Henrique Jatai Batista, Andreia Ferreira De Castro Gomes, Alexandre Magno Rodrigues Teixeira, Hélcio Silva Dos Santos   +17 more
wiley   +1 more source

Remimazolam-flumazenil provides fast recovery from general anesthesia compared to propofol during radiofrequency catheter ablation of atrial fibrillation

Scientific Reports
The optimal anesthetic agent for radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) and its impact on the recovery profiles remain uncertain.
Seohee Lee, Jaemoon Lee, So Yeong Hwang, Jae-Woo Ju, Karam Nam, Hyo-Jeong Ahn, So-Ryoung Lee, Eue-Keun Choi, Yunseok Jeon, Youn Joung Cho   +9 more
doaj   +1 more source

Successful use of ketamine in reversing the paradoxical reactions to midazolam after failing flumazenil [PDF]

Pediatric Emergency Medicine Journal
Midazolam is generally effective and safe to be widely used in the management of seizures, procedural sedation, and anxiolytic. However, paradoxical reactions, though rare, present clinical challenges. Flumazenil is the preferred option for reversing the
Abdullah Nasser Aldosari, Sinan Alnashi
doaj   +1 more source

Correspondence of Basal Forebrain Resting‐State Functional Connectivity and Cerebral Glucose Metabolism Alterations With Neurotransmitter Maps in Alzheimer's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Altered functional connectivity of basal forebrain subregions (Ch1‐3, Ch4) and widespread cerebral hypometabolism were identified in Alzheimer's disease using simultaneous PET/MRI. Spatial correspondence with normative neurotransmitter receptor and transporter maps suggested that serotonergic and dopaminergic systems may contribute to AD‐related ...
Yujie He, Hanxiao Xue, Sheng Bi, Yan Wang, Xiaocao Liu, Yixia Li, Zhigeng Chen, Dongdong Rong, Bixiao Cui, Jie Ma, Shaozhen Yan, Jie Lu   +11 more
wiley   +1 more source

The GABA_A-Benzodiazepine Receptor Antagonist Flumazenil Abolishes the Anxiolytic Effects of the Active Constituents of Crocus sativus L. Crocins in Rats

Molecules, 2020
Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented.
Nikolaos Pitsikas, Petros A. Tarantilis
doaj   +1 more source

Analgesic Effect of Safranal in Animal Model of Acute Pain; Possible role of the GABAergic Pathway

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: There are reports for analgesic, anti-inflammatory, hypnotic, neuroprotective and anti-oxidative effects of safranal. The aim of this study was to investigate the analgesic effects of safranal using acute pain method in rat and ...
Esmael Izadpanah, Elham Saei, Omid Abdollahi, Abbas Ahmadi, Mohammad Raman Moloudi   +4 more
doaj