GABA deficiency in NF1: a multimodal [11C]-Flumazenil and spectroscopy study [PDF]
, 2016 Objective: To provide a comprehensive investigation of the GABA system in patients with Neurofibromatosis type 1 (NF1) that allows understanding the nature of the GABA imbalance in humans at pre- and post-synaptic levels. Methods: In this cross-sectional
Abrunhosa, AJ +6 more
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NeuroImage, 2020 The use of hybrid PET/MR imaging facilitates the simultaneous investigation of challenge-related changes in ligand binding to neuroreceptors using PET, while concurrently measuring neuroactivation or blood flow with MRI. Having attained a steady state of
Jörg Mauler +12 more
doaj +1 more source
Comparison of postoperative nausea and vomiting between remimazolam and propofol: a propensity score-matched, retrospective, observational, single-center cohort study [PDF]
Korean Journal of Anesthesiology, 2023 Background Remimazolam is a novel ultrashort-acting benzodiazepine that has recently become available for general anesthesia. However, the incidence of postoperative nausea and vomiting (PONV) associated with remimazolam remains unknown.
Yuji Suzuki +4 more
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Reducing risk of overdose with midazolam injection in adults: an evaluation of change in clinical practice to improve patient safety in England [PDF]
, 2014 Rationale aims and objectives. This study sought to evaluate potential reductions in risk associated with midazolam injection, a sedating medication, following a United Kingdom National Patient Safety Alert.
Abeysekera1 +15 more
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Antagonistic effect of flumazenil on tiletamine-zolazepam-induced anaesthesia in Beagle dogs
Veterinární Medicína, 2018 Benzodiazepines exert hypnotic/sedative effects through their inhibitory actions on the γ-aminobutyric acid receptor type A. Since flumazenil antagonises these effects through competitive inhibition of the receptor, it has been used to reverse the effect
J.Y. Lee +4 more
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Flavonoids as GABAA receptor ligands: the whole story? [PDF]
, 2012 Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects that they produce, such as sedation, myorelaxation, ataxia, amnesia, and ethanol and barbiturate ...
Marder, Nora Mariel +1 more
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Gamma oscillations in V1 are correlated with GABA(A) receptor density: A multi-modal MEG and Flumazenil-PET study. [PDF]
, 2015 High-frequency oscillations in the gamma-band reflect rhythmic synchronization of spike timing in active neural networks. The modulation of gamma oscillations is a widely established mechanism in a variety of neurobiological processes, yet its ...
Bouet, R. +8 more
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Behavioral Sciences, 2022 Background: Generalised anxiety disorder (GAD) is a common anxiety disorder associated with social and occupational impairment. Recently, a theory was postulated that dysfunctional gamma aminobutyric acid type A receptors (GABAA) are implicated in ...
Alexander T. Gallo +7 more
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Flumazenil does not improve hepatic encephalopathy associated with acute ischemic liver failure in the rabbit [PDF]
, 1990 The effect of flumazenil, a benzodiazepine antagonist, on hepatic encephalopathy was studied in rabbits with acute hepatic failure induced by a two-stage liver devascularization procedure.
Knegt, R.J. (Robert) de +4 more
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Risperidone in a child with untractable emergency delirium: a case report [PDF]
Korean Journal of Anesthesiology, 2016 A 6-year-old boy was scheduled for thoracic magnetic resonance imaging under deep sedation with midazolam 1.8 mg and propofol 100 µg/kg/min via intravenous injection. He showed emergence delirium in the post-anesthesia care unit.
Young Hee Shin +2 more
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