Results 31 to 40 of about 8,785 (193)
Frontiers in Neuroscience, 2023 IntroductionThe fMRI BOLD response to emotional stimuli highlighting the role of the medial prefrontal cortex (MPFC) has been thoroughly investigated.
Alexander Heinzel +17 more
doaj +1 more source
Antagonistic effect of flumazenil on tiletamine-zolazepam-induced anaesthesia in Beagle dogs
Veterinární Medicína, 2018 Benzodiazepines exert hypnotic/sedative effects through their inhibitory actions on the γ-aminobutyric acid receptor type A. Since flumazenil antagonises these effects through competitive inhibition of the receptor, it has been used to reverse the effect
J.Y. Lee +4 more
doaj +1 more source
Flumazenil-insensitive kavain potentiation has less-than-additive effect on diazepam action.
, 2016 Top, Representative traces demonstrating responses to control (10 μM GABA); control and 1 μM diazepam; control, 1 μM diazepam and 10 μM flumazenil; control and 10 μM flumazenil; control and 300 μM kavain; control, 300 μM kavain and 10 μM flumazenil; and ...
Anders A. Jensen (709631) +7 more
core +1 more source
Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil
Frontiers in Psychiatry, 2022 IntroductionSince the 1990s there has been evidence of the significant role Flumazenil (FLU) has in benzodiazepines (BZD) detoxes. The Verona Detox approach has been developed for high dose BZD and Z-drug detoxification via continuous subcutaneous ...
Rebecca Casari +6 more
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Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The majority of symptoms and signs of acute diazepam poisoning are the consequence of its sedative effect on the CNS affecting selectively polisynaptic routes by stimulating inhibitory action of GABA.
Šegrt Zoran +7 more
doaj +1 more source
Treatment of zolpidem poisoning with flumazenil in a cat [PDF]
, 2023 This report aims to describe the case of a cat intoxicated with zolpidem that was treated with flumazenil. Flumazenil is an imidazodiazepine that effectively reverses the central effects of benzodiazepines.
Gomes, Viviane Horta +3 more
core
Flumazenil: A Benzodiazepine Antagonist
, 1990 Although benzodiazepines have been proven safe and effective for the induction and maintenance of sedation, some instances require the reversal of these events prior to the natural process of metabolism and elimination.
Gaylene B. Tsipis +1 more
core +1 more source
[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. [PDF]
PLoS ONE, 2012 Evidence indicates that synchronization of cortical activity at gamma-band frequencies, mediated through GABA-A receptors, is important for perceptual/cognitive processes.
W Gordon Frankle +8 more
doaj +1 more source
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by altered synaptic connectivity and network organization, resulting in profound impairments in social communication and interaction. Transcranial direct current stimulation (tDCS) represents a promising approach to modulate maladaptive plasticity associated with ASD;
Antonia Ramme +9 more
wiley +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source