Flumazenil; Intoxicació; BenzodiazepinesFlumazenil; Intoxicación; BenzodiacepinasFlumazenil; Intoxication; BenzodiazepinesArticle sobre el flumazenil: antídot específic per revertir la depressió del sistema nerviós central (SNC) causada per una ...
Grup de Treball Xarxa d’Antídots +2 more
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Background/AimsFlumazenil was administered after the completion of endoscopy under sedation to reduce recovery time and increase patient safety. We evaluated patient satisfaction after endoscopy under sedation according to the timing of a postprocedural ...
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Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam. [PDF]
ABSTRACT Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiety while improving patient acceptance and procedural quality. In Japan, benzodiazepines such as midazolam and opioid analgesics have long been widely used in routine clinical practice; however, many of these agents historically
Ichijima R +13 more
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Remimazolam for Zephyr Endobronchial Valve Placement in a Severe Chronic Obstructive Pulmonary Disease Patient: A Case Report. [PDF]
ABSTRACT Remimazolam‐based general anesthesia provided stable hemodynamics and rapid, clear emergence in a patient with severe chronic obstructive pulmonary disease undergoing Zephyr endobronchial valve placement, suggesting that remimazolam may be a feasible anesthetic option for this procedure in patients with limited cardiopulmonary reserve.
Morimoto T +7 more
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Is the Precipitation of Anxiety Symptoms Associated with Bolus Doses of Flumazenil a Barrier to Its Use at Low Continuous Doses in Benzodiazepine Withdrawal? [PDF]
Introduction: Benzodiazepines (BZDs) are used in the management of anxiety and sleep disorders; however, chronic use is associated with tolerance and dependence. During withdrawal, symptoms of anxiety are often severe and problematic for patients and may
Alexander Gallo +9 more
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Comparison of Remimazolam-Flumazenil and Propofol on Psychomotor Function and Emergence Following General Anesthesia in Surgical Abortion: A Randomized Controlled Trial [PDF]
Jinye Gu,1,* Yang Liu,1,* Xiaoyan Lin,1 Lei Fu,1 Jianbo Liu,1 Bona Sun,2 Xiaoyu Li,3 Bo Lu3 1Department of Anesthesiology, Zhenhai Hospital of Traditional Chinese Medicine, Ningbo, 315200, People’s Republic of China; 2Department of Gynaecology ...
Gu J +7 more
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INTRODUCTION: Benzodiazepines (BZD) are a class of anxiolytics with varying uses, which primarily act on the GABAA receptor resulting in hyperpolarisation.
Hulse, GK +4 more
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Flumazenil-Insensitive Benzodiazepine Effects in Recombinant αβ and Neuronal GABAA Receptors
Gamma-aminobutyric acid, type A (GABAA) receptors are complex heterogeneous pentamers with various drug binding sites. Several lines of evidence suggest that benzodiazepines modulate certain GABAA receptors in a flumazenil-insensitive manner, possibly ...
Jing-Jing Lian +4 more
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Clinical studies have demonstrated that the γ-aminobutyric acid type A (GABAA) receptor complex plays a central role in the modulation of anxiety.
Shiou-Shiow Farn +5 more
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Re-audit of the use of flumazenil following midazolam-induced conscious sedation
Introduction Flumazenil is an antagonist drug of Benzodiazepam (BDZ) that has been used as a reversal agent of midazolam-induced conscious sedation (CS) in both emergency and elective procedures.
Muhammad Syafiq Asyraf Rosli +1 more
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