Results 21 to 30 of about 8,172 (206)

Bolus infusion scheme for the adjustment of steady state [11C]Flumazenil levels in the grey matter and in the blood plasma for neuroreceptor imaging

NeuroImage, 2020
The use of hybrid PET/MR imaging facilitates the simultaneous investigation of challenge-related changes in ligand binding to neuroreceptors using PET, while concurrently measuring neuroactivation or blood flow with MRI. Having attained a steady state of
Jörg Mauler, Alexander Heinzel, Andreas Matusch, Hans Herzog, Irene Neuner, Jürgen Scheins, Christine Wyss, Jürgen Dammers, Markus Lang, Johannes Ermert, Bernd Neumaier, Karl-Josef Langen, N. Jon Shah   +12 more
doaj   +1 more source

Antagonistic effect of flumazenil on tiletamine-zolazepam-induced anaesthesia in Beagle dogs

Veterinární Medicína, 2018
Benzodiazepines exert hypnotic/sedative effects through their inhibitory actions on the γ-aminobutyric acid receptor type A. Since flumazenil antagonises these effects through competitive inhibition of the receptor, it has been used to reverse the effect
J.Y. Lee, S.J. Son, S. Jang, S. Choi, D.W. Cho   +4 more
doaj   +1 more source

Long-Term Management of Generalised Anxiety Disorder with Low-Dose Continuous Infusions of Flumazenil: A Case Series

Behavioral Sciences, 2022
Background: Generalised anxiety disorder (GAD) is a common anxiety disorder associated with social and occupational impairment. Recently, a theory was postulated that dysfunctional gamma aminobutyric acid type A receptors (GABAA) are implicated in ...
Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Sean D. Hood, Hans Stampfer, Gary K. Hulse   +7 more
doaj   +1 more source

Risperidone in a child with untractable emergency delirium: a case report [PDF]

Korean Journal of Anesthesiology, 2016
A 6-year-old boy was scheduled for thoracic magnetic resonance imaging under deep sedation with midazolam 1.8 mg and propofol 100 µg/kg/min via intravenous injection. He showed emergence delirium in the post-anesthesia care unit.
Young Hee Shin, Seung Hyeon Lee, Dae Yoon Kim   +2 more
doaj   +1 more source

In vivo Illustration of Altered Dopaminergic and GABAergic Systems in Early Parkinson's Disease

Frontiers in Neurology, 2022
BackgroundChanges in γ-aminobutyric acid (GABA) function are noted in patients with Parkinson's disease (PD) who have some non-motor impairments. However, dopamine-related GABA function and GABA-related cognitive changes are still unclear.MethodsThirteen
Hirotsugu Takashima, Hirotsugu Takashima, Tatsuhiro Terada, Tatsuhiro Terada, Tomoyasu Bunai, Takashi Matsudaira, Takashi Matsudaira, Tomokazu Obi, Yasuomi Ouchi, Yasuomi Ouchi   +9 more
doaj   +1 more source

Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiety while improving patient acceptance and procedural quality. In Japan, benzodiazepines such as midazolam and opioid analgesics have long been widely used in routine clinical practice; however, many of these agents historically
Ryoji Ichijima, Masahiro Toyama, Taiki Shishido, Yuki Koyo, Takehiro Yoshii, Reona Kawamura, Tsubasa Ishikawa, Yasuhiko Mizuguchi, Naoya Toyoshima, Hiroyuki Takamaru, Masayoshi Yamada, Masau Sekiguchi, Seiichiro Abe, Yutaka Saito   +13 more
wiley   +1 more source

Benzodiazepine poisoning in elderly [PDF]

Vojnosanitetski Pregled, 2016
Background/Aim. Benzodiazepines are among the most frequently ingested drugs in self-poisonings. Elderly may be at greater risk compared with younger individuals due to impaired metabolism and increased sensitivity to benzodiazepines. The aim of
Perković-Vukčević Nataša, Vuković-Ercegović Gordana, Šegrt Zoran, Đorđević Snežana, Jović-Stošić Jasmina   +4 more
doaj   +1 more source

Field immobilisation of adult Weddell seals using intramuscular butorphanol and midazolam

Veterinary Record, Volume 199, Issue 3, Page e142-e146, 1/8 August 2026.
Abstract Background When working with free‐ranging phocid seals, methods of chemical immobilisation require ongoing refinement to reduce complications, particularly apnoea, during research procedures. Methods Adult Weddell seals (n = 20) at Cape Crozier, Antarctica, were chemically immobilised with intramuscular injection of butorphanol and midazolam ...
Rachel R. Holser, Rachel P. Hickcox, Daniel P. Costa, Thomas Hildebrand, Sarah P. Flanagan, Michelle A. LaRue   +5 more
wiley   +1 more source

Successful replacement of the urinary bladder following exteriorisation during bite‐induced scrotal trauma in a domestic rabbit (Oryctolagus cuniculus)

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Scrotal exteriorisation of abdominal viscera is rarely reported in domestic rabbits and constitutes a surgical emergency. This report describes traumatic inguinoscrotal herniation of the urinary bladder in a domestic rabbit (Oryctolagus cuniculus), a 4‐month‐old entire male, following bite‐induced scrotal avulsion during territorial aggression.
Delcio Almeida Magalhães, Ana Beatriz Portes Gonçalves, Milena Aimi Taguchi, Maria Jaqueline Mamprim de Arruda Monteiro, Sheila Canevese Rahal   +4 more
wiley   +1 more source

Long‐term management of extensive plastron thermal burn with surgical debridement and negative pressure wound therapy in an African spurred tortoise (Centrochelys sulcata)

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract An adult, male African spurred tortoise (Centrochelys sulcata) was presented for evaluation of severe thermal burns of the plastron, approximately 5 months after an enclosure fire. On presentation, limbs were ulcerated, and the plastron was soft to touch with necrotic tissue and purulent discharge.
Hannah A. Danks, Gretel Tovar‐Lopez, Jasmine Sarvi, Oscar Chavez, João Brandão, Nicky Cassel   +5 more
wiley   +1 more source