Results 61 to 70 of about 4,036 (152)
Flunarizine attenuates cocaine-induced inhibition of A9 dopaminergic neurons
, 1991 The intravenous administration of cocaine (0.5-8 mg/kg) produced a dose-related inhibition of the firing rate of substantia nigra (A9) dopaminergic (DA) neurons.
Pani L. +4 more
core +1 more source
Migraine and Restless Legs Syndrome: A Meta‐Analysis
Journal of Sleep Research, Volume 35, Issue 3, June 2026.ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio +8 more
wiley +1 more source
Amelioration of ischaemic brain damage by postischaemic treatment with flunarizine
, 1985 The effect of flunarizine, a calcium entry blocker, on ischaemic damage was investigated using a new model of forebrain ischaemia. Fasted rats were subjected to nine minutes ischaemia and one week recovery.
Deshpande, J. K., Wieloch, T.
core +1 more source
Journal of Pharmaceutical Analysis, 2013 A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column (50mmÃ4.6mm i.d., 1.9μm ...
Niamh OâConnor +3 more
doaj +1 more source
Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy
Epilepsia, Volume 67, Issue 5, Page 2628-2653, May 2026.Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan +23 more
wiley +1 more source
Hormonal and Metabolic Changes Induced by Flunarizine Therapy: Preliminary Results
, 1985 The effect of 30-days of flunarizine (5 mg/day) therapy on pituitary, B-pancreatic, gonadic and adrenal function was studied in five adolescents with common migraine.
Tommaso Sacquegna +9 more
core +1 more source
Delayed urticaria during treatment with anti‐CGRP monoclonal antibodies in migraine
Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1193-1199, May 2026.Abstract Objective To characterize clinical presentation and management of urticaria associated with calcitonin gene‐related peptide (CGRP) ‐targeting monoclonal antibodies (mAbs) for migraine prophylaxis. Background CGRP‐targeting mAbs are effective in migraine prophylaxis, but have been associated with hypersensitivity reactions, including urticaria.
Christoph T. Berger +5 more
wiley +1 more source
Flunarizine and α-adrenergic responses in isolated canine saphenous veins
, 1987 1. Experiments were designed to determine how flunarizine affects contractions of cutaneous veins to α-adrenergic activation. 2. Rings of canine saphenous vein were mounted at optimal length for isometric tension recording in organ chambers filled with ...
Flavahan, NA +3 more
core +1 more source
Arquivos de Neuro-Psiquiatria, 1997 Fourty-five migraine without aura patients underwent a parallel double-blind trial aiming the comparison of the effects of propranolol 60 mg/day to flunarizine 10 mg/day and to propranolol 60 mg/day plus flunarizine 10 mg/day simultaneously. There were 3
Carlos Alberto Bordini +3 more
doaj +1 more source
Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses
VirusesLassa fever (LF), a viral hemorrhagic fever disease with a case fatality rate that can be over 20% among hospitalized LF patients, is endemic to many West African countries.
Chukwudi A. Ofodile +10 more
doaj +1 more source