Results 51 to 60 of about 4,036 (152)

Missense Variants in the A Isoform of FGF13 as a Novel Cause of Paroxysmal Dyskinesia

Movement Disorders, Volume 41, Issue 7, Page 1884-1892, July 2026.
Abstract Background Pathogenic variants within the unique N‐terminal inactivation particle of FGF13 isoform A (FGF13A) have so far been associated only with an X‐linked dominant epileptic encephalopathy (DEE). Objective The aim was to expand the clinical and molecular spectrum of FGF13A‐related disorder.
Cyril Mignot, Matthildi Athina Papathanasiou Terzi, Claudia Ravelli, Elisabeth Bosch, Xueqin Lin, Adeline Trauffler, Roseline Caumes, Andrew E. Fry, Clementine Fort, Gaelle Gauthe, Regina Trollmann, Thomas Wirth, Mathieu Anheim, Aurélie Méneret, Emmanuel Roze, Jean‐Madeleine de Sainte Agathe, Hailan He, Eleni Panagiotakaki, Gaëtan Lesca, André Reis, Diane Doummar, Thomas Smol, Georgia Vasileiou   +22 more
wiley   +1 more source

CGRP‐Targeted Therapy in Vestibular Migraine—How Strong Is the Evidence?

European Journal of Neurology, Volume 33, Issue 7, July 2026.
ABSTRACT Background Medications for migraine prevention targeting the calcitonin gene‐related peptide (CGRP) pathway have substantially reduced symptom burden in many patients that have failed previous treatment strategies. In contrast, data on treatment response to monoclonal antibodies (mAbs) or small molecule receptor antagonists (gepants) in ...
Alexander Andrea Tarnutzer, Patricia Castro Abarca, Diego Kaski   +2 more
wiley   +1 more source

Navigating the Complexity of Alternating Hemiplegia in Childhood: A Comprehensive Review

Rambam Maimonides Medical Journal
Alternating hemiplegia of childhood (AHC) is a complex neurodevelopmental disorder characterized by paroxysmal and transient events of unilateral or bilateral paresis, usually occurring before 18 months of age.
Jamir Pitton Rissardo, Nilofar Murtaza Vora, Yogendra Singh, Sweta Kishore, Ana Letícia Fornari Caprara   +4 more
doaj   +1 more source

Effectiveness of galcanezumab versus topiramate, amitriptyline, and other select traditional oral migraine preventives with evidence of efficacy: 3‐Month results from the TRIUMPH study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1525-1536, July/August 2026.
Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi, Cristina Tassorelli, Manjit Matharu, Taoufik Alsaadi, Carlos Vallarino, Lars Viktrup, Maurice Vincent, Rebecca L. Robinson   +7 more
wiley   +1 more source

Dehydrative Allylic Amination in Water via a Polymer‐Supported Ruthenium Catalyst

ChemSusChem, Volume 19, Issue 12, 26 June 2026.
A green and rapid synthesis of allylamines is achieved using a polymer‐supported ruthenium catalyst. This dehydrative reaction between allyl alcohols and amines proceeds entirely in water without organic solvents or inert gas. The process completes in just 1 h, and the solid catalyst allows for easy filtration, offering a sustainable route to valuable ...
Shota Mizuno, Yasuhiro Kubota, Toshiyasu Inuzuka, Kazumasa Funabiki, Munenori Inoue   +4 more
wiley   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1383-1398, June 2026.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Observation of the therapeutic effect of flunarizine capsules combined with the Epley manoeuvre in the treatment of benign paroxysmal positional vertigo

Annals of Human Biology
Background The Epley manoeuvre is the standard treatment for benign paroxysmal positional vertigo (BPPV) and flunarizine shows potential in vertigo-related disorders, however, evidence on their combined use remains limited.Aim This retrospective study ...
Yongjun Zhu, Hao Zhou, Dachuan Fan, Xiaobo Li, Jianming Yang   +4 more
doaj   +1 more source

B Vitamins Supplement Potentiates Antiparkinsonian Effect of Flunarizine: the Behavioral and Biochemical Evidences From 6-Hydroxydopamine Animal Model [PDF]

Journal of Kerman University of Medical Sciences, 2018
Introduction: Prominent data indicate that flunarizine (flu), a calcium channel blocker, has neuroprotective effect. However, several authors have reported that the chronic use of flu can produce drug-induced Parkinsonism.
Mohamad Sofiabadi, Hashem Haghdoost-Yazdi, Hossein Piri, Mohamad Esmaeili   +3 more
doaj  

Course of Alternating Hemiplegia of Childhood

Pediatric Neurology Briefs, 2011
The natural history and long-term outcome of alternating hemiplegia of childhood (AHC) was studied by questionnaire within a large cohort of 157 patients, as part of the European Network for Research on Alternating Hemiplegia (ENRAH) project.
J Gordon Millichap
doaj   +1 more source

Headache with Benign Alternating Hemiplegia

Pediatric Neurology Briefs, 2004
An 8-year-old boy with benign familial nocturnal alternating hemiplegia of childhood (BNAHC) and severe headache and vomiting during episodes is reported from the University of Rochester, NY.
J Gordon Millichap
doaj   +1 more source