Results 71 to 80 of about 4,036 (152)
Spectral EEG Analysis and Flunarizine Treatment in Migraine Patients
, 1988 Spectral EEG analysis has been successfully utilized in previous studies on migraine patients. The aim of our study was to evaluate, by means of EEG mapping, potential correlations between the efficacy of flunarizine treatment in migraine patients and ...
Rita Formisano +6 more
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Trials, 2009 Background Many studies have already reported encouraging results in the prophylactic therapy of migraine by acupuncture, but there seems to be a lack of high quality randomized controlled trials from China.
Li Jingdao +5 more
doaj +1 more source
Dystroglycan clustering in cells treated chloranil and flunarizine dihydrochloride.
, 2013 A. Primary astrocytes were treated for 7 h with 20 nM laminin-1alone, 20 nM laminin-1 and 15 µM chloranil or 20 nM laminin-1 and15 µM flunarizine during the last 4 h. The chemical structures of chloranil and flunarizine are represented. B, C.
Sarah Stevenson (355059) +2 more
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National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Epilepsy is a common neurological disorder but the mechanism of seizure generation has been only partially unraveled. Currently available antiepileptics have a low therapeutic index and furthermore, provide satisfactory seizures control in ...
Raina Jain, Naveen Bankey, Ashish Jain
doaj +1 more source
Neuroendocrine effects of flunarizine treatment in postmenopausal women.
, 1985 Flunarizine (10 mg/day for 60 days) was given to eight postmenopausal women with common migraine. Plasma LH pulsatility fluctuation, peripheral concentrations of prolactin (PRL), cortisol, beta-endorphin (beta-EP), beta-lipotropin (beta-LPH) and Pain ...
M. G. Morgillo +20 more
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F1000Research, 2015 Objective: To determine the exact role of sodium channel proteins in migration, invasion and metastasis and understand the possible anti-invasion and anti-metastatic activity of repurposed drugs with voltage gated sodium channel blocking properties ...
Tomas Koltai
doaj +1 more source
Circumvention of Gefitinib Resistance by Repurposing Flunarizine via Histone Deacetylase Inhibition
, 2023 Gefitinib is an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) for treating advanced non-small cell lung cancer (NSCLC). However, drug resistance seriously impedes the clinical efficacy of gefitinib.
James C. H. Chow +7 more
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Inhibition of PyAeADHII at 70°C by flunarizine dihydrochloride.
, 2013 The assay was performed with 260 nM PyAeADHII in 50 mM NaPO4 pH 7.5, 3 mM α-tetralone, 0.3 mM NADPH in the presence of 80–1200 µM flunarizine dihydrochloride in DMSO/isopropanol.
Annalisa Vitale (418239) +7 more
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Flunarizine effects on oxidative stress in migraine patients
, 2004 Prophylactic activity of flunarizine in migraine is attributed to its antioxidant properties and to the relief of cerebral vasospasm in which nitric oxide (NO) is involved.
CIANCARELLI, IRENE +4 more
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Prolactin response to bromocriptine in flunarizine treated migrainous women.
, 1997 Flunarizine, a calcium channel blocker, is widely used in migraine prophylaxis. Although an antidopaminergic effect has been suggested for this drug, it is unclear whether the antimigraine action of flunarizine involves the dopaminergic system.
Bernardi G. +6 more
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