Results 181 to 190 of about 40,790 (312)

Genome‐wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target

open access: yesiMeta, EarlyView.
This study identifies the uncharacterized gene C9ORF50 as a novel regulator of immune evasion. Functioning as an intrinsically disordered protein, C9ORF50 drives liquid‐liquid phase separation to facilitate spliceosome assembly and maintain RNA splicing fidelity.
Tong Shao   +24 more
wiley   +1 more source

Biofilm Analysis by Confocal Microscopy—Basics and Practical Aspects

open access: yesMicroscopy Research and Technique, EarlyView.
Development and detachment of an interfacial microbial community. The resulting biofilms and bio‐aggregates are three‐dimensional communities susceptible to examination by confocal laser scanning microscopy. ABSTRACT This review is intended as a guideline for beginners in confocal laser scanning microscopy.
Thomas R. Neu, Ute Kuhlicke
wiley   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara   +3 more
wiley   +1 more source

Diffusion studies through fluorescence recovery after photobleaching in hydrated polyamides

open access: green, 2010
N. B. Hatzigrigoriou   +4 more
openalex   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

open access: yesSmall, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira   +9 more
wiley   +1 more source

Use of metabolomics and fluorescence recovery after photobleaching to study the bioavailability and intestinal mucus diffusion of polyphenols from cauliflower waste

open access: green, 2015
Gerard Bryan Gonzales   +7 more
openalex   +2 more sources

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