Results 121 to 130 of about 283,224 (387)

Development of a 3D Human Colon Model Along with Bioelectronics for the Induction and Monitoring of Diseases

open access: yesAdvanced Science, EarlyView.
We present a functional three‐dimensional in‐vivo‐mimicking human colon (3D‐IVM‐HC) model engineered via Freeform Reversible Embedding of Suspended Hydrogels bioprinting with gelatin methacrylate (GelMA)/alginate hydrogels. This 3D non‐animal model replicates crypt‐like architectures, epithelial polarization, and stromal–tumor interactions, showing ...
Jorge Alfonso Tavares‐Negrete   +7 more
wiley   +1 more source

Study of the antimutagenic effects of plant polyphenols under the action of genotoxicants

open access: yesJournal of Education, Health and Sport, 2019
In the test of dominant lethal germ cell mutations in male rats, the effect of phenobarbital and fluorouracil genotoxicants and their combined administration with the biotrit-C preparation, obtained from wheat seedlings and containing plant polyphenols ...
V. S. Ivanov
doaj  

Lenvatinib Plus Paclitaxel as Second‐Line Therapy for Advanced Gastric Cancer Patients: A Dose Escalation Exploratory Study

open access: yesAdvanced Science, EarlyView.
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou   +8 more
wiley   +1 more source

Clinical evaluation of cancer chemotherapy with 5-fluorouracil [PDF]

open access: bronze, 1961
V. K. Vaitkevicius   +4 more
openalex   +1 more source

Quantification and expert evaluation of evidence for chemopredictive biomarkers to personalize cancer treatment. [PDF]

open access: yes, 2017
Predictive biomarkers have the potential to facilitate cancer precision medicine by guiding the optimal choice of therapies for patients. However, clinicians are faced with an enormous volume of often-contradictory evidence regarding the therapeutic ...
Beckman, Robert A.   +8 more
core   +1 more source

Interpretable Multimodal Fusion Model Enhances Postoperative Recurrence Prediction in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
An interpretable multimodal fusion model (RSA) integrating clinical, radiomic, and pathomic features is developed and validated to predict early postoperative recurrence in gastric cancer. The RSA model demonstrates superior predictive performance and holds potential for guiding adjuvant chemotherapy decisions and improving individualized patient ...
Ping'an Ding   +16 more
wiley   +1 more source

Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors [PDF]

open access: bronze, 1969
John J. Costanzi   +2 more
openalex   +1 more source

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