Results 121 to 130 of about 174,614 (242)

Takotsubo Cardiomyopathy in a Patient Undergoing 5-Fluorouracil Infusion: Considerations for Folinic Acid, 5-Fluorouracil, and Oxaliplatin (FOLFOX) Cardiotoxicity and Rechallenge. [PDF]

Cureus
Sami N, Raizada A, Phillip GJ, Rana D, Alishetti S.   +4 more
europepmc   +1 more source

Tumor Hypoxia and CD8+ T‐Cell Infiltration in Patients With Advanced Laryngeal Cancer

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective We assessed correlations between tumor carbonic anhydrase IX (CAIX) staining, as a marker of tumor hypoxia, and CD8+ T‐cell infiltration in a cohort of patients with advanced laryngeal squamous cell carcinoma undergoing a bioselection approach for definitive treatment. Study Design Retrospective cohort study.
Joshua D. Smith, Elizabeth Gensterblum‐Miller, David W.A. Forner, Pratyusha Yalamanchi, Marisa R. Buchakjian, Steven B. Chinn, Andrew G. Shuman, Keith A. Casper, Kelly M. Malloy, Chaz L. Stucken, Scott A. Mclean, Michelle L. Mierzwa, Jennifer Shah, Paul L. Swiecicki, Francis P. Worden, Mark E.P. Prince, Matthew E. Spector, J. Chad Brenner, Molly E. Heft Neal   +18 more
wiley   +1 more source

[Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ. [PDF]

Oncol Lett
Mhaidat NM, Bouklihacene M, Thorne RF.
europepmc   +1 more source

Clinicopathological and molecular characterization of KRAS wild‐type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes

The Journal of Pathology, EarlyView.
Abstract Pancreatic ductal adenocarcinomas (PDACs) with wild‐type KRAS constitute a small fraction of PDACs, and these tumors were recently shown to harbor frequent actionable oncogenic mutations and fusions. However, the clinicopathological features of KRAS wild‐type PDAC have not been well studied.
Kazuhiro Toriyama, Katsuhiro Masago, Noriko Shibata, Masataka Haneda, Takamichi Kuwahara, Seiji Natsume, Shota Kobayashi, Yasuko Fujita, Eiichi Sasaki, Kenji Yamao, Hiroki Kawashima, Yasuhiro Shimizu, Kazuo Hara, Yasushi Yatabe, Waki Hosoda   +14 more
wiley   +1 more source

Treatment of Intermediate‐Risk Hepatoblastoma Using a Combined Cisplatin and Doxorubicin (PLADO) Regimen and Optimized Surgical Resection

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Complete resection of the primary tumor is critical for the survival of children with hepatoblastomas (HBs). This prospective clinical study aimed to clarify the outcome of a chemotherapy regimen comprising cisplatin and doxorubicin (PLADO) followed by definitive surgery conducted at the appropriate time in patients with ...
Tomoro Hishiki, Kohmei Ida, Kenichiro Watanabe, Makiko Mori, Junya Fujimura, Yuki Nogami, Tomoko Iehara, Ken Hoshino, Akiko Yokoi, Shohei Honda, Takuro Kazama, Masahiro Sekiguchi, Norihiko Kitagawa, Risa Matsumura, Motonari Nomura, Yohei Yamada, Ryo Hanaki, Hide Kaneda, Yuichi Takama, Takeshi Inoue, Yukichi Tanaka, Osamu Miyazaki, Hiroki Nagase, Tetsuya Takimoto, Kenichi Yoshimura, Eiso Hiyama   +25 more
wiley   +1 more source

Systemic chemotherapy in patients with unresectable pseudomyxoma peritonei from low-grade appendiceal mucinous neoplasms: a case series. [PDF]

J Gastrointest Oncol
Vierra M, Morgan RB, Ostowari A, Turaga KK, Shergill A, Eng OS.   +5 more
europepmc   +1 more source

Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Colorectal cancer (CRC) accounts for 10% of cancer cases worldwide; however, pediatric CRC is extremely rare, with an annual incidence of one to two cases per million. Microsatellite instability (MSI) has been shown to play a relevant prognostic role in adult CRC. Corresponding data for pediatric CRC are lacking. This study examines
Hannah Wild, Alexandra Liebmann, Lucas Maennel, Linda Maschke, Andreas Block, Leo Kager, Udo Kontny, Abbas Agaimy, Michaela Kuhlen, Antje Redlich, Andreas Schmidt, Jörg Fuchs, Dominik T. Schneider, Ines B. Brecht, Michael Abele   +14 more
wiley   +1 more source

Risk factors for fluorouracil-induced cardiotoxicity in patients with gastrointestinal tumor. [PDF]

Front Cardiovasc Med
Wu Y, Lv C, Li J, Ma Y, Zhu X.
europepmc   +1 more source

Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Oxaliplatin‐induced peripheral neuropathy (OIPN) is a major clinical challenge because it leads to discontinuation of chemotherapy. Omeprazole, a proton pump inhibitor (PPI), has been shown to prevent OIPN in a rat model. Therefore, we aimed to test whether the concomitant use of a PPI reduces oxaliplatin discontinuation due to OIPN.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Hibiki Kudamatsu, Shunsuke Fujita, Mayako Uchida, Takaaki Yamada, Nobuaki Egashira, Ichiro Ieiri, Satoru Koyanagi, Shigehiro Ohdo, Takao Shimazoe, Daisuke Kobayashi   +14 more
wiley   +1 more source

Targeting the Odontogenic Keratocysts: Therapeutic Potential of 5-Fluorouracil Through Thymidylate Synthase Inhibition. [PDF]

Cureus
Reddy GV, Reddy GSP, Priyatham V, Veeravalli JJ, Kocherlakota S.   +4 more
europepmc   +1 more source