Results 141 to 150 of about 283,224 (387)

Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda   +3 more
wiley   +1 more source

Discrepancy Between Radiographic and Pathological Response Assessment in Neoadjuvant Treatment for Pancreatic Cancer: A Comparison Between Neoadjuvant Chemotherapy and Neoadjuvant Chemoradiotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study investigated the association between radiographic and pathological response assessments among patients with pancreatic cancer receiving neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy. The present study revealed that discrepancies between radiographic and histological responses may differ according to the type of therapy ...
Satoru Miyahara   +8 more
wiley   +1 more source

Significance of Neoadjuvant S‐1‐Based Chemotherapy for Older Patients With Locally Advanced Gastric Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Neoadjuvant chemotherapy (NAC) has been extensively developed for locally advanced gastric cancer (GC). In Asia, S‐1‐based regimens, such as docetaxel, oxaliplatin, and S‐1 (DOS) and S‐1 and oxaliplatin (SOX), are expected to become the standard of care.
Kota Kawabata   +9 more
wiley   +1 more source

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.

open access: yesNew England Journal of Medicine, 2004
H. Hurwitz   +14 more
semanticscholar   +1 more source

Future of 5-fluorouracil in cancer therapeutics, current pharmacokinetics issues and a way forward [PDF]

open access: yes, 2019
Abd-Rabou   +39 more
core   +1 more source

Association Between the Degree of Arterial Contact Angle and Survival in Patients With Borderline Resectable Pancreatic Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study evaluated the prognostic impact of arterial contact angle in patients with borderline resectable pancreatic cancer undergoing neoadjuvant therapy and surgery. An arterial contact angle of ≥ 90° was associated with higher R1 resection rates and worse survival outcomes.
Katsuhisa Ohgi   +8 more
wiley   +1 more source

Impact of Sarcopenia During Induction Treatment in Patients With Unresectable Locally Advanced Pancreatic Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Chemotherapeutic advances have increased opportunities for conversion surgery (CS) in unresectable locally advanced (UR‐LA) pancreatic cancer (PC). However, the optimal indications for CS remain unclear. Sarcopenia has been associated with poor outcomes in PC, except UR‐LA PC. Herein, we aimed to evaluate the impact of sarcopenia on
Sho Uemura   +8 more
wiley   +1 more source

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa   +5 more
wiley   +1 more source

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