Protective Effect of Oleuropein on 5-Fluorouracil-Induced Ovarian Damage [PDF]
Background: 5-fluorouracil is one of the chemotherapy drugs that has destructive effects on body tissues such as the heart, liver, kidney, brain and reproductive system in humans and animals. Reproductive dysfunction is considered to be an important side
Mahshid Khajavi+3 more
doaj
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate, 5-fluorouracil, and prednisone in solid tumors [PDF]
James D. Bearden+9 more
openalex +1 more source
Clinical Evidence for Three Distinct Gastric Cancer Subtypes: Time for a New Approach [PDF]
Bearzi Italo+10 more
core +1 more source
Abstract Background The optimal regimen and chemotherapy intensity are still under investigation for neoadjuvant treatment of locally advanced rectal cancer (LARC). The CinClare trial has demonstrated improved pathologic complete response (pCR) with the addition of irinotecan to neoadjuvant chemoradiotherapy (CRT) guided by uridine diphosphate ...
Zhen Zhang+24 more
wiley +1 more source
Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma [PDF]
P. Seifert+3 more
openalex +1 more source
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu+4 more
wiley +1 more source
Studies on 5-Fluorouracil-containing Ribonucleic Acid
Ivan I. Kaiser+2 more
openalex +1 more source
A controlled study of combined 1,3-bis-(2-chloroethyl)-1-nitrosourea and 5-fluorouracil therapy for advanced gastric and pancreatic cancer [PDF]
John S. Kovach+4 more
openalex +1 more source
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade+4 more
wiley +1 more source