Results 201 to 210 of about 142,003 (296)

A Word of Caution: Watch and Wait in the Total Mesorectal Excision Era

ANZ Journal of Surgery, EarlyView.
Among 573 patients undergoing long‐course neoadjuvant chemoradiotherapy and total mesorectal excision between 2006 and 2020, five‐year overall survival was 85.7%. Local recurrence was 3.4% and metastatic recurrence was 16.5%. Pathological stage and tumour regression grade stratified long‐term outcomes, providing regional benchmarks for evaluating organ‐
K. Broughton, R. Cohen, A. Armanios, S. Jamin, E. Eguare, H. Yoo, G. Lim, E. Maclean, M. Teoh, M. Nyandoro, M. H. Wallace, J. Ryan   +11 more
wiley   +1 more source

Effective management of 5-fluorouracil-induced coronary vasospasm allowing chemotherapy continuation: a single-center observational study. [PDF]

Cardiooncology
Kolossváry K, Heltai K, Székely B, Rubovszky G.   +3 more
europepmc   +1 more source

Chemotherapy resistance and risk stratification in gestational trophoblastic neoplasia: A systematic review and network meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Higher pretreatment β‐hCG, greater tumor burden, higher FIGO stage/score, and choriocarcinoma were associated with higher chemoresistance risk in gestational trophoblastic neoplasia. In exploratory network analyses, etoposide‐containing regimens showed lower predicted chemoresistance.
Ying‐Ying Xue, Xin‐Yue Yang, Fang‐Yu Chen, Hui‐Ting Yang, Chao Zhang, Jin‐Zhu Yan, Shi‐Shi Wu, Long Wang   +7 more
wiley   +1 more source

Beware the Ides of Chemotherapy: A Report on Hyperammonemic Encephalopathy Induced by FOLFOX-6 (5-Fluorouracil, Leucovorin, and Oxaliplatin). [PDF]

Cureus
Ts S, Balaji S, K D, S K, Ts K, Subramanian Y, Paul AJ, Adalarasan S, N J, C H.   +9 more
europepmc   +1 more source

Longitudinal changes in bleb morphology following the PAUL Glaucoma Implant visualized using ultrasonography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate bleb morphology longitudinally using sonography following glaucoma drainage device (GDD) surgery. Methods Prospective observational cohort study conducted from January 2022 to March 2024, with follow‐up up to 12 months postoperatively. Bleb morphology, including superior and inferior bleb height, transverse and longitudinal
Constance Liegl, Benjamin Aretz, Leonie Bourauel, Pascal Schipper, Carolin Deubel, Lilli Joussen, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca   +9 more
wiley   +1 more source

Local Injections of Fluorouracil for Eyelid Hordeolum. [PDF]

Plast Reconstr Surg Glob Open
Qin M, Liang Y, Su X, Zhuang J, Zhang Z, Chai H, Hu J.   +6 more
europepmc   +1 more source

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

Acta Ophthalmologica, EarlyView.
Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical ...
Koen A. van Overdam, J. Sebag
wiley   +1 more source

Juniperus phoenicea extract-loaded nanostructured lipid carriers for potent antimicrobial and anticancer combination therapy. [PDF]

AMB Express
Ismail PA, Elwakil BH, Hagar M, Olama ZA.   +3 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source