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ABSTRACT Background Patients with gastrointestinal cancer often present reduction in functional capacity and develop frailty, which increases the risk of chemotherapy intolerance. We investigated whether physical frailty is associated with early intolerance to CAPOX (capecitabine+oxaliplatin) in patients with colon, rectal, or gastric cancer.
Isabella Pellegrini Grama Pereira Lima +9 more
wiley +1 more source
Phase II randomised study of magrolimab combined with bevacizumab-FOLFIRI in patients with previously treated advanced inoperable metastatic colorectal cancer. [PDF]
Fakih M +19 more
europepmc +1 more source
Design, synthesis, molecular docking and cytotoxic evaluation of novel pyrimidine-based sulfonamide derivatives as potent anticancer agents: SAR insights and biological profiling. [PDF]
Bayoumy NM +3 more
europepmc +1 more source
Histological Response and Prognostic Factors in Gastric Adenocarcinoma Treated With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT) Chemotherapy: A Retrospective Single-Center Study. [PDF]
Pereira H +5 more
europepmc +1 more source
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Annals of Pharmacotherapy, 1994
OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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Archives of Dermatology, 1969
A patient with actinic keratoses was treated with three different fluorouracil preparations topically without the development of reaction. Purposeful exposure to hot sunlight failed to cause any inflammation even though he was applying the fluorouracil at this time.
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A patient with actinic keratoses was treated with three different fluorouracil preparations topically without the development of reaction. Purposeful exposure to hot sunlight failed to cause any inflammation even though he was applying the fluorouracil at this time.
openaire +2 more sources

