Results 181 to 190 of about 142,003 (296)

Epithelial interferon-stimulated gene programs modulate chemotherapy sensitivity in colorectal cancer via EPSTI1. [PDF]

Oncogene
Erkan EP, Hämäläinen E, Kolikova J, Nikupaavola T, Sajnani K, Kuc K, Ojala K, Kukkonen M, Hermelo I, Kurttila A, Koskensalo S, Tarvainen T, Leppä A, Keränen I, Haapamäki C, Karjalainen E, Carpelan-Holmström M, Renkonen-Sinisalo L, Koskenvuo L, Puolakkainen P, Mecklin JP, Väyrynen JP, Virolainen E, iCAN, Nykter M, Aaltonen LA, Urbanucci A, Lepistö A, Ristimäki A, Seppälä TT.   +29 more
europepmc   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

Prediction of benefit from docetaxel chemotherapy for HR-positive breast cancer in the PACS-01 trial. [PDF]

Breast
Penault-Llorca F, Lusque A, Filleron T, Tran K, Du L, Baehner R, Dalenc F, Lacroix-Triki M, Bachelot T, Andre F, Boucher P, Lemonnier J, Symmans WF.   +12 more
europepmc   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Acute toxicity and genotoxicity assessment of environmental contaminants using <i>Artemia salina</i>. [PDF]

Arh Hig Rada Toksikol
Aleksić JĐ, Gačić L, Kračun-Kolarević M, Marić JJ, Vuković-Gačić B, Kolarević S.   +5 more
europepmc   +1 more source

Effects of Lymphatic and Venous Invasion Status on Postoperative Prognosis and Metastasis Pattern in Patients With Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study

World Journal of Surgery, EarlyView.
Lymphovascular invasion (LVI) is a recognized predictor of poor postoperative outcomes in patients with esophageal squamous cell carcinoma (ESCC). However, only a few studies have evaluated lymphatic invasion (LI) and venous invasion (VI) separately across contemporary perioperative strategies.
Nao Kitasaki, Yoichi Hamai, Yuta Ibuki, Naoto Kishi, Manato Ohsawa, Tomoaki Kurokawa, Morihito Okada   +6 more
wiley   +1 more source

HopeFOL, or FOL of problems? Leucovorin for autistic symptoms. [PDF]

Oncologist
Holle LM, Kratz J, Dow-Hillgartner EN, Patel MA, Deming D, Uboha N, Lubner S, LoConte NK.   +7 more
europepmc   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

[Expression of Concern] Fatty acids inhibit anticancer effects of 5-fluorouracil in mouse cancer cell lines. [PDF]

Oncol Lett
Tanabe E, Kitayoshi M, Fujii K, Ohmori H, Luo Y, Kadochi Y, Mori S, Fujiwara R, Nishiguchi Y, Sasaki T, Kuniyasu H.   +10 more
europepmc   +1 more source

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott, Eugene Moylan, Maree Colosimo, Giles Stratton, Thomas Chiu, Mahsa H. Kouhkamari, Maureen Hitschfeld, Jessica Michie, Richard De Boer   +8 more
wiley   +1 more source