Results 101 to 110 of about 105,140 (274)

Interventions for treating depression after stroke [PDF]

open access: yes, 2008
Background: Depression is an important consequence of stroke that impacts on recovery yet is often not detected or inadequately treated. This is an update of a Cochrane review first published in 2004.
Agnoli   +254 more
core   +1 more source

Fluoxetine and diazepam acutely modulate stress induced-behavior.

open access: yesBehavioural Brain Research, 2016
Drug residue contamination in aquatic ecosystems has been studied extensively, but the behavioral effects exerted by the presence of these drugs are not well known. Here, we investigated the effects of acute stress on anxiety, memory, social interaction,
A. C. Giacomini   +9 more
semanticscholar   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Impacts of early intervention with fluoxetine following early neonatal immune activation on depression-like behaviors and body weight in mice [PDF]

open access: yes
Several reports have suggested that early neonatal immune activation adversely influences the hypothalamic– pituitary–adrenal (HPA) axis development in humans and animal models.
امانی, محمد   +6 more
core   +1 more source

Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression

open access: yesInternational Journal of Neuropsychopharmacology, 2016
Background: Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression.
Ren‐Hong Du   +5 more
semanticscholar   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Fluoxetine Dose and Administration Method Differentially Affect Hippocampal Plasticity in Adult Female Rats

open access: yesNeural Plasticity, 2014
Selective serotonin reuptake inhibitor medications are one of the most common treatments for mood disorders. In humans, these medications are taken orally, usually once per day. Unfortunately, administration of antidepressant medications in rodent models
Jodi L. Pawluski   +6 more
doaj   +1 more source

Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test [PDF]

open access: yes, 2018
Galanin N-terminal fragment (1-15) [GAL(1-15)] modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist in the forced swimming test (FST) and the binding characteristics and mRNA levels of 5-HT1AR in the dorsal hippocampus ...
Borroto-Escuela, Dasiel O.   +8 more
core  

Early intervention combined with targeted treatment promotes cognitive and behavioral improvements in young children with fragile x syndrome. [PDF]

open access: yes, 2012
Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability due to an expansion in the full mutation range (>200 CGG repeats) of the promoter region of the FMR1 gene leading to gene silencing.
Borodyanskara, Mariya   +3 more
core   +3 more sources

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal   +7 more
wiley   +1 more source

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