Results 31 to 40 of about 18,308 (279)

Analysis of Foot and Mouth Disease Virus Polyprotein for Multi Peptides Vaccine Design: An In silico Strategy

Journal of Pure and Applied Microbiology, 2022
Foot-and-mouth disease virus (FMDV) is small RNA virus from Picornaviridae family; genus Aphthovirus. FMDV causes maximum levels of infectivity in cattle and harmful socioeconomic effects. The present report attempted to design vaccine candidate from the
Ranya Mohmed Sid Ahmed, Yassir A. Almofti, Khoubieb Ali Abd-elrahman   +2 more
doaj   +1 more source

RING finger protein 5 is a key anti-FMDV host factor through inhibition of virion assembly. [PDF]

PLoS Pathog
Zhang W, Li W, Yang Y, Cao W, Shao W, Huang M, Wang J, Chen Z, Cai J, Liu H, Zhao X, Dong X, Zhou T, Tian H, Zhu Z, Yang F, Zheng H.   +16 more
europepmc   +2 more sources

A Single Dose of Dendrimer B₂T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection

Vaccines, 2020
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals whose control relies on efficient vaccination. We have reported that dendrimer peptide B2T, with two copies of FMDV B-cell epitope VP1 (136−154) linked ...
Rodrigo Cañas-Arranz, Mar Forner, Sira Defaus, Patricia de León, María J. Bustos, Elisa Torres, Francisco Sobrino, David Andreu, Esther Blanco   +8 more
doaj   +1 more source

Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish, Carolina Stenfeldt, Rachel M. Palinski, Steven J. Pauszek, Jonathan Arzt   +4 more
doaj   +1 more source

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

Journal of Veterinary Research, 2021
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of
El Nahas Abeer F., Abd El Naby Walaa S.H., Khatab Shymaa A., Fergany Al-Zahraa A., Rashed Rashed R.   +4 more
doaj   +1 more source

Effect of heat on foot-and-mouth disease virus (FMDV) in the components of milk from FMDV-infected cows [PDF]

Journal of Hygiene, 1976
SUMMARYFoot-and-mouth disease virus (FMDV) survived in skim milk, cream and the pelleted cellular debris components of milk obtained from FMDV-infected cows after pasteurization at 72°C for 0·25 min. Virus was recovered from whole milk of infected cows after that milk was heated at 72°C. for 5 min.
J. H. Blackwell, J. L. Hyde
openaire   +3 more sources

The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood

npj Vaccines, 2020
Foot and mouth disease (FMD) is a highly contagious viral disease with high economic impact, representing a major threat for cloven-hooved mammals worldwide.
L. Jouneau, D. Lefebvre, F. Costa, A. Romey, S. Blaise-Boisseau, A. Relmy, Y. Jaszczyszyn, Cloelia Dard-Dascot, S. Déjean, Nicolas Versillé, E. Guitton, P. Hudelet, M. Curet, K. De Clercq, L. Bakkali-Kassimi, S. Zientara, B. Klonjkowski, I. Schwartz-Cornil   +17 more
semanticscholar   +1 more source

The Carrier Conundrum; A Review of Recent Advances and Persistent Gaps Regarding the Carrier State of Foot-and-Mouth Disease Virus

Pathogens, 2020
The existence of a prolonged, subclinical phase of foot-and-mouth disease virus (FMDV) infection in cattle was first recognized in the 1950s. Since then, the FMDV carrier state has been a subject of controversy amongst scientists and policymakers.
Carolina Stenfeldt, Jonathan Arzt
doaj   +1 more source

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

PLoS Pathogens, 2020
The type I interferon response is an important innate antiviral pathway. Recognition of viral RNA by RIG-I-like receptors (RLRs) activates a signaling cascade that leads to type I interferon (IFN-α/β) gene transcription.
L. Visser, Chiara Aloise, Kirby N. Swatek, G. Medina, K. Olek, H. Rabouw, R. D. de Groot, M. Langereis, T. de Los Santos, D. Komander, T. Skern, F. V. van Kuppeveld   +11 more
semanticscholar   +1 more source

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration [PDF]

Journal of Cell and Molecular Research, 2016
An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1.
Maziar Habibi-Pirkoohi, Saeid Malekzadeh-Shafaroudi, Hasan Marashi, Saeid Zibaee, Afsaneh Mohkami, Saba NejatizaXeh   +5 more
doaj   +1 more source