Results 81 to 90 of about 7,938 (206)

Detection of Foot-and-Mouth Disease Virus in Swine Meat Juice

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) is a highly contagious agent that impacts livestock industries worldwide, leading to significant financial loss. Its impact can be avoided or minimized if the virus is detected early. FMDV detection relies on vesicular
Sean Yeo, Ming Yang, Martin Nyachoti, Rolf Rauh, Johnny D. Callahan, Charles Nfon   +5 more
doaj   +1 more source

Glycosylated Foot‐And‐Mouth Disease Virus‐Like Particles Produced in Pichia Pastoris Enhance Stability and Immunogenicity

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
An N‐glycosylation was strategically introduced at the 166th position of VP1 via artificial mutagenesis. The glycans mainly consist of high‐mannose type, significantly enhancing the stability and uptake of VLPs. The glycosylated VLPs conferred a robust Th1‐type immune response in mice and pigs and provided 100% protection against FMDV in pigs ...
Zhiyao Li, Hu Dong, Shuanghui Yin, Manyuan Bai, Zhidong Teng, Lingbo Chen, Suyu Mu, Yun Zhang, Yaozhong Ding, Shiqi Sun, Huichen Guo   +10 more
wiley   +1 more source

Advances in Foot-and-Mouth Disease Virus Proteins Regulating Host Innate Immunity

Frontiers in Microbiology, 2020
Foot-and-mouth disease (FMD) is a highly contagious disease that affects cloven-hoofed animals such as pigs, cattle, and sheep. The disease is caused by the foot-and-mouth disease virus (FMDV) which has a non-enveloped virion with icosahedral symmetry ...
Jiangling Peng, Jiamin Yi, Wenping Yang, Jingjing Ren, Yuan Wen, Haixue Zheng, Dan Li   +6 more
doaj   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Dendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle. [PDF]

PLoS ONE, 2017
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A synthetic vaccine candidate consisting of dendrimeric peptides harbouring two copies of a B-epitope [VP1(136-154)] linked to a T-cell epitope [3A(21-35 ...
Ivana Soria, Valeria Quattrocchi, Cecilia Langellotti, Mariela Gammella, Sebastian Digiacomo, Beatriz Garcia de la Torre, David Andreu, Maria Montoya, Francisco Sobrino, Esther Blanco, Patricia Zamorano   +10 more
doaj   +1 more source

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhonghui Zhang, Xuesai Li, Qingli Niu, Jinming Wang, Yanghe Liu, Dossêh Jean Apôtre Afayibo, Wenting Chen, Songlin Yang, Hong Yin, Guiquan Guan, Jifei Yang   +10 more
wiley   +1 more source

Apigenin Restricts FMDV Infection and Inhibits Viral IRES Driven Translational Activity [PDF]

Viruses, 2015
Foot-and-mouth disease (FMD) is a highly contagious disease of domestic and wild ruminants that is caused by FMD virus (FMDV). FMD outbreaks have occurred in livestock-containing regions worldwide. Apigenin, which is a flavonoid naturally existing in plant, possesses various pharmacological effects, including anti-inflammatory, anticancer, antioxidant ...
Qian, Suhong, Fan, Wenchun, Qian, Ping, Zhang, Dong, Wei, Yurong, Chen, Huanchun, Li, Xiangmin   +6 more
openaire   +3 more sources

Japanese Encephalitis Virus Genotype 5 Infectious Clone and Reporter System for Antiviral Evaluation

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT The recent emergence of Japanese encephalitis virus genotype 5 (JEV5) has raised concerns regarding limited vaccine efficacy. Here, we report the construction of a full‐length infectious cDNA clone of JEV5 using a bacterial artificial chromosome (BAC) system, based on a South Korea isolate, K15P38 strain.
Jae‐Yeon Park, Wataru Kamitani, Hyun‐Jin Shin, Hye‐Mi Lee   +3 more
wiley   +1 more source

Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Amplified genome using RT‐PCR with the new primer pair. ABSTRACT Bovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi, Tatsuya Nishi, Kazuki Morioka, Katsuhiko Fukai   +3 more
wiley   +1 more source

Molecular Detection of FMDV Serotype A Isolated from the Egyptian Delta During 2019-2020 [PDF]

, 2022
Gawhara Ahmed-Abdelmonem, Zeinab R. Aboezz, Ahmed Habashi, Saad Sharawi   +3 more
openalex   +1 more source