Results 1 to 10 of about 1,361 (119)

Incorporation of PEG Diacrylates (PEGDA) Generates Hybrid Fmoc-FF Hydrogel Matrices [PDF]

Gels, 2022
Generated by a hierarchical and multiscale self-assembling phenomenon, peptide-based hydrogels (HGs) are soft materials useful for a variety of applications. Short and ultra-short peptides are intriguing building blocks for hydrogel fabrication.
Elisabetta Rosa, Enrico Gallo, Teresa Sibillano, Cinzia Giannini, Serena Rizzuti, Eliana Gianolio, Pasqualina Liana Scognamiglio, Giancarlo Morelli, Antonella Accardo, Carlo Diaferia   +9 more
doaj   +12 more sources

Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines [PDF]

Pharmaceutics, 2023
Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently proposed as alternative supramolecular vehicles for the delivery of biologically relevant molecules like anticancer drugs and contrast agents. The inner compartment of
Giovanni Smaldone, Elisabetta Rosa, Enrico Gallo, Carlo Diaferia, Giancarlo Morelli, Mariano Stornaiuolo, Antonella Accardo   +6 more
doaj   +5 more sources

Ultrashort Cationic Peptide Fmoc-FFK as Hydrogel Building Block for Potential Biomedical Applications [PDF]

Gels, 2023
Fmoc-diphenylalanine (Fmoc-FF) is a low-molecular-weight peptide hydrogelator. This simple all-aromatic peptide can generate self-supporting hydrogel materials, which have been proposed as novel materials for diagnostic and pharmaceutical applications ...
Enrico Gallo, Carlo Diaferia, Sabrina Giordano, Elisabetta Rosa, Barbara Carrese, Gennaro Piccialli, Nicola Borbone, Giancarlo Morelli, Giorgia Oliviero, Antonella Accardo   +9 more
doaj   +5 more sources

Fmoc-FF Nanogel-Mediated Delivery of Doxorubicin and Curcumin in Thyroid Cancer Cells [PDF]

Pharmaceutics
Background: Thyroid cancer (TC) is the most prevalent endocrine malignancy, and is categorized into well-differentiated and aggressive anaplastic types. Novel therapeutic modalities are needed for TC.
Enrico Gallo, Giovanni Smaldone, Luca Cimmino, Mariantonia Braile, Francesca Maria Orlandella, Neila Luciano, Antonella Accardo, Giuliana Salvatore   +7 more
doaj   +5 more sources

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies [PDF]

Gels
This study reports the development of peptide-based hydrogels for the encapsulation and controlled release of peptide nucleic acids in drug delivery applications.
Sabrina Giordano, Monica Terracciano, Enrico Gallo, Carlo Diaferia, Andrea Patrizia Falanga, Antonella Accardo, Monica Franzese, Marco Salvatore, Gennaro Piccialli, Nicola Borbone, Giorgia Oliviero   +10 more
doaj   +5 more sources

From Unprintable Peptidic Gel to Unstoppable: Transforming Diphenylalanine Peptide (Fmoc-FF) Nanowires and Cellulose Nanofibrils into a High-Performance Biobased Gel for 3D Printing. [PDF]

ACS Appl Bio Mater
The growing interest in gel-based additive manufacturing, also known as three-dimensional (3D) gel-printing technology, for research underscores the crucial need to develop robust biobased materials with excellent printing quality and reproducibility ...
Dalloul F, Mietner JB, Raveendran D, Chen S, Barba E, Möck DMJ, Hubel F, Sochor B, Koyiloth Vayalil S, Hesse L, Olbrich A, Appelt J, Müller-Buschbaum P, Roth SV, Navarro JRG.   +14 more
europepmc   +7 more sources

Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells and diagnostic applications [PDF]

Scientific Reports
Dexamethasone (DEX) is a synthetic analogue of cortisol commonly used for the treatment of different pathological conditions, comprising cancer, ocular disorders, and COVID-19 infection.
Enrico Gallo, Carlo Diaferia, Giovanni Smaldone, Elisabetta Rosa, Giovanni Pecoraro, Giancarlo Morelli, Antonella Accardo   +6 more
doaj   +5 more sources

Fmoc-Diphenylalanine Hydrogels: Optimization of Preparation Methods and Structural Insights [PDF]

Pharmaceuticals, 2022
Hydrogels (HGs) are tri-dimensional materials with a non-Newtonian flow behaviour formed by networks able to encapsulate high amounts of water or other biological fluids.
Carlo Diaferia, Elisabetta Rosa, Giancarlo Morelli, Antonella Accardo   +3 more
doaj   +4 more sources

Nanoscale Piezoelectric Properties of Self-Assembled Fmoc-FF Peptide Fibrous Networks [PDF]

ACS Applied Materials & Interfaces, 2015
Fibrous peptide networks, such as the structural framework of self-assembled fluorenylmethyloxycarbonyl diphenylalanine (Fmoc-FF) nanofibrils, have mechanical properties that could successfully mimic natural tissues, making them promising materials for ...
Beirne, J., Buchete, N. -V., Guyonnet, J., Kholkin, A. L., Kilpatrick, J. I., Redmond, G., Rodriguez, B. J., Ryan, K.   +7 more
core   +7 more sources

Evaluation of cationic peptide-based nanogels as delivery systems for negatively charged molecules: a formulative study [PDF]

Scientific Reports
Peptide-based nanogels (NGs) represent a cutting-edge class of nanoscale drug delivery systems. Due to their structural properties, NGs platforms can encapsulate and protect therapeutic agents (e.g.
Mariangela Rosa, Elisabetta Rosa, Valeria Castelletto, Ian W. Hamley, Giancarlo Morelli, Antonella Accardo, Carlo Diaferia   +6 more
doaj   +2 more sources