Results 21 to 30 of about 1,380 (137)

Multicomponent Peptide-Based Hydrogels Containing Chemical Functional Groups as Innovative Platforms for Biotechnological Applications

open access: yesGels, 2023
Multicomponent hydrogels (HGs) based on ultrashort aromatic peptides have been exploited as biocompatible matrices for tissue engineering applications, the delivery of therapeutic and diagnostic agents, and the development of biosensors.
Sabrina Giordano   +9 more
doaj   +1 more source

Multicomponent Hydrogel Matrices of Fmoc‐FF and Cationic Peptides for Application in Tissue Engineering

open access: yesMacromolecular Bioscience, 2022
AbstractIn the last years, peptide‐based hydrogels are being increasingly used as suitable matrices for biomedical and pharmaceutical applications, including drug delivery and tissue engineering. Recently, the synthesis and the gelation properties of a small library of cationic peptides, containing a Lys residue at the C‐terminus and derivatized with ...
Rosa E.   +9 more
openaire   +4 more sources

Fmoc-diphenylalanine-based hydrogels as a potential carrier for drug delivery

open access: yese-Polymers, 2020
High concentrations of IDM drugs can be incorporated into hydrogels during the self-assembly of Fmoc-FF. Small amounts of PAMAM added to the hydrogel (Fmoc-FF 0.5%–IDM 0.5%–PAMAM 0.03%) resulted in more prolonged IDM release when compared with Fmoc-FF 0 ...
Choe Ranjoo, Il Yun Seok
doaj   +1 more source

Poly(acrylic acid)/Dipeptide Double-Network Hydrogel to Achieve a Highly Stretchable Strain Sensor

open access: yesChemosensors, 2022
Flexible and stretchable strain sensors can be applied for human health monitoring and disease diagnoses via the output of multiple biophysical signals. However, it is still a challenge to fabricate short-peptide-based strain sensors. Here, we prepared a
Xin Luo, Boya Ding, Xingcen Liu
doaj   +1 more source

Revisiting the Self-Assembly of Highly Aromatic Phenylalanine Homopeptides

open access: yesMolecules, 2020
Diphenylalanine peptide (FF), which self-assembles into rigid tubular nanostructures, is a very short core recognition motif in Alzheimer’s disease β-amyloid (Aβ) polypeptide.
Enric Mayans, Carlos Alemán
doaj   +1 more source

Self-Supporting Hydrogels Based on Fmoc-Derivatized Cationic Hexapeptides for Potential Biomedical Applications

open access: yesBiomedicines, 2021
Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia   +6 more
doaj   +1 more source

Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes

open access: yesScientific Reports, 2021
We report here the use of a nanofibrous hydrogel as a 3D scaffold for the culture and maintenance of functional primary human hepatocytes. The system is based on the cooperative assembly of a fiber-forming peptide component, fluorenylmethyloxycarbonyl ...
Douglas MacPherson   +3 more
doaj   +1 more source

Hierarchical self-assembly of di-, tri- and tetraphenylalanine peptides capped with two fluorenyl functionalities: from polymorphs to dendrites [PDF]

open access: yes, 2016
Homopeptides with 2, 3 and 4 phenylalanine (Phe) residues and capped with fluorenylmethoxycarbonyl and fluorenylmethyl esters at the N-terminus and C-terminus, respectively, have been synthesized to examine their self-assembly capabilities.
Alemán Llansó, Carlos   +9 more
core   +2 more sources

Self-assembly of diphenylalanine with preclick components as capping groups [PDF]

open access: yes, 2017
Alkyne and azide, which are commonly used in the cycloaddition reaction recognized as “click chemistry”, have been used as capping groups of two engineered diphenylalanine (FF) derivatives due to their ability to form weak intermolecular interactions (i ...
Alemán Llansó, Carlos   +8 more
core   +2 more sources

Short-Peptide Supramolecular Hydrogels for In Situ Growth of Metal–Organic Framework-Peptide Biocomposites [PDF]

open access: yes, 2023
The development of bio-MOFs or MOF biocomposites through the combination of MOFs with biopolymers offers the possibility of expanding the potential applications of MOFs, making use of more environmentally benign processes and reagents and giving rise to ...
Carmona Fernández, Francisco Jesús   +7 more
core   +1 more source

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