Stem Cell Research & Therapy, 2022 Background Mesenchymal-based therapy has been utilized as a practical approach in the treatment of renal ischemia/reperfusion (I/R) injury. However, low cell retention and survival in the ischemic site have remained challenging issues. To bridge this gap,
Haniyeh Najafi +5 more
doaj +1 more source
Thermally-controlled spherical peptide gel architectures prepared using the pH switch method [PDF]
, 2023 Self-assembling nanostructured peptide gels are promising materials for sensing, drug delivery, and energy harvesting. Of particular interest are short diphenylalanine (FF) peptides modified with 9-fluorenylmethyloxycarbonyl (Fmoc), which promotes the ...
Alam, Mir Waqas +7 more
core +2 more sources
Self-assembly of Fmoc-tetrapeptides based on the RGDS cell adhesion motif [PDF]
, 2011 Self-assembly in aqueous solution has been investigated for two Fmoc [Fmoc ¼ N-(fluorenyl)-9-methoxycarbonyl] tetrapeptides comprising the RGDS cell adhesion motif from fibronectin or the scrambled sequence GRDS.
Alemán, Carlos +8 more
core +1 more source
Incorporation of Natural and Recombinant Collagen Proteins within Fmoc-Based Self-Assembling Peptide Hydrogels [PDF]
, 2022 Hydrogel biomaterials mimic the natural extracellular matrix through their nanofibrous ultrastructure and composition and provide an appropriate environment for cell–matrix and cell–cell interactions within their polymeric network.
Bella, Jordi +5 more
core +2 more sources
Advanced Science, 2019 Peptidomimetic low‐molecular‐weight hydrogelators, a class of peptide‐like molecules with various backbone amide modifications, typically give rise to hydrogels of diverse properties and increased stability compared to peptide hydrogelators.
Vasantha Basavalingappa +9 more
doaj +1 more source
Supramolecular fibers in gels can be at thermodynamic equilibrium : a simple packing model reveals preferential fibril formation versus crystallization [PDF]
, 2016 Low molecular weight gelators are able to form nanostructures, typically fibers, which entangle to form gel-phase materials. These materials have wide-ranging applications in biomedicine and nanotechnology.
Halling, Peter J. +3 more
core +1 more source
Fmoc solid-phase synthesis of RF9 optimization with mass spectrometry verification
Current Issues in Pharmacy and Medical Sciences, 2022 The RF9 compound, which is an antagonist of the FF neuropeptide receptors is used as a therapeutic substance to improve the effectiveness of opioids in the chronic treatment of pain.
Orocz Marta +4 more
doaj +1 more source
Morphology Diversity of L‐Phenylalanine‐Based Short Peptide Supramolecular Aggregates and Hydrogels [PDF]
, 2018 Supramolecular aggregates and hydrogels of diverse morphologies can be obtained by replacing the widely studied aromatic N‐capping of phenylalanine derivatives by long alkyl chains. Simple changes in chain length and number of phenylalanine residues lead
Escuder, Beatriu, Martí-Centelles, Rosa
core +1 more source
Using experimental and computational energy equilibration to understand hierarchical self-assembly of Fmoc-dipeptide amphiphiles [PDF]
, 2016 Despite progress, a fundamental understanding of the relationships between the molecular structure and self-assembly configuration of Fmoc-dipeptides is still in its infancy.
Hunt, Neil +6 more
core +1 more source
Injectable Magnetic-Responsive Short-Peptide Supramolecular Hydrogels: Ex Vivo and In Vivo Evaluation [PDF]
, 2021 This study was supported by project FIS2017-85954-R funded by MCIN/AEI/10.13039/501100011033/FEDER "Una manera de hacer Europa", Spain, grants FIS PI20/0317 and ICI19/00024 (BIOCLEFT) (MINECO, Instituto de Salud Carlos III, Spain, cofinanced by FEDER ...
Alaminos, Miguel +13 more
core +3 more sources