Results 91 to 100 of about 10,642 (179)

Toward peptide-based protein replacement in fragile X syndrome: Evaluating the N-tat strategy

Medicine in Drug Discovery
Fragile X syndrome (FXS), a leading inherited cause of intellectual disability and autism, arises from loss of the RNA-binding protein FMRP and consequent dysregulation of synaptic mRNA translation.
Oliver A. Kent
doaj   +1 more source

Acao de Varios Agentes sobre o Efeito Paralisante dos Membros Posteriores Induzido pela Crotamina em Camundongos

Bioscience Journal, 2006
A crotamina, neurotoxina isolada a partir da peçonha de Crotalus durissus terrificus (cascavel sul-americana), foi a primeira proteína estudada no Brasil sob o aspecto bioquímico e farmacológico.
Carlos Alberto Vieira, Lucas de Oliveira Vieira, Joao Julio Rosa Bueno, Maira Renata Michelutti Debiasi, Adriana Cristina Mancim, Jose Roberto Giglio   +5 more
doaj  

The role of FMR1 mRNA structure on the efficiency of non-canonical translation of toxic polyglycine protein. [PDF]

Nucleic Acids Res
Niewiadomska D, Piasecka A, Baud A, Broniarek I, Sobczak K.   +4 more
europepmc   +1 more source

Mis-spliced FMR1 transcripts in human fragile X syndrome neural progenitors and neurons. [PDF]

J Neurodev Disord
Hourani SM, Utami KH, Oh SL, Castrén ML, Pouladi MA.   +4 more
europepmc   +1 more source

GABAergic neurons exhibit subtype-specific changes in the developing somatosensory cortex of a rat model of Fragile X Syndrome. [PDF]

Front Neurosci
Sumera A, Crichton A, Kind PC, Sibley C, Booker SA.   +4 more
europepmc   +1 more source

FMRP and its many partners [PDF]

Nature Reviews Neuroscience, 2003
openaire   +1 more source

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target. [PDF]

Neuron
Suresh A, Kourdougli N, Nomura T, Buth JE, Miranda-Rottmann S, Sánchez-León CA, Wu MW, Nelson SM, Wall LT, Tran AT, Araya R, Contractor A, Gandal MJ, Portera-Cailliau C.   +13 more
europepmc   +1 more source

<i>Fmr1</i> Deletion and Early-Life Stress Interact to Increase Cell Proliferation and Glial Populations at the Expense of Immature Neurons in the Adult Dentate Gyrus. [PDF]

Int J Mol Sci
Latchney SE, Ominuta JE, Smitha LEL, Blandin KJ, Lugo JN.   +4 more
europepmc   +1 more source

Mapping RNA-Binding Proteins on the Ribosome by Tethered Micrococcal Nuclease. [PDF]

Biochemistry
Yao CY, Joseph S.
europepmc   +1 more source

A cultura na FMRP-USP

Medicina (Ribeirão Preto), 2002
Maria Alice Nunes Coelho, Anette Hoffmann   +1 more
openaire   +3 more sources