Results 51 to 60 of about 14,329 (173)

Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].

PLoS ONE, 2012
Fragile X syndrome is caused by the absence of the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein. FMRP is associated with messenger RiboNucleoParticles (mRNPs) present in polyribosomes and its absence in neurons leads to alteration ...
Rachid El Fatimy, Sandra Tremblay, Alain Y Dury, Samuel Solomon, Paul De Koninck, John W Schrader, Edouard W Khandjian   +6 more
doaj   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

SnapShot: FMRP mRNA targets and diseases

, 2014
FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which
Pasciuto, E, Bagni, C, BAGNI, CLAUDIA
core   +1 more source

FMRP 1C3 Western Blot (Millipore MAB2160) post-IP v1

, 2015
Protocol for using Mouse-FMRP antibody follow immunoprecipitation of FMRP using a rabbit antibody such as Abcam #17722

core   +1 more source

NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP

Molecular Brain, 2019
Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and Moloney Leukemia Virus 10 (MOV10) protein in ...
Preeti Madhav Kute, Sarayu Ramakrishna, Nagammal Neelagandan, Sumantra Chattarji, Ravi. S. Muddashetty   +4 more
doaj   +1 more source

Lichenoid and Granulomatous Stomatitis: Three Additional Cases and Detailed Immunohistochemical Analysis

Journal of Cutaneous Pathology, Volume 53, Issue 12, Page 1074-1079, December 2026.
ABSTRACT Background Lichenoid and granulomatous stomatitis (LGS) is a rare condition, with clinicopathological features resembling lichenoid and granulomatous dermatitis. Despite increasing reports, its etiology remains unclear and detailed immunohistochemical (IHC) studies are lacking.
Mariana Paravani Palaçon, Karina Kendelhy Santos, Karina Helen Martins, Cecília Aparecida de Oliveira Campos, Ana Terezinha Marques Mesquita, Evânio Vilela Silva, Thales Peres Candido Moreira, Gabriel Enrique Tantalean Laor, Victor Hugo Toral‐Rizo, Alan Grupioni Lourenço, Heitor Albergoni Silveira, Jorge Esquiche León, Andreia Bufalino   +12 more
wiley   +1 more source

: Link between FMRP/RISC/PB/SG

, 2008
International audienceThe fragile X mental retardation protein (FMRP) is an RNA-binding protein involved in the mRNA metabolism. The absence of FMRP in neurons leads to alterations of the synaptic plasticity, probably as a result of translation ...
Subramanian, Murugan, Mandel, Jean-Louis, Marie-Cécile Didiot, Murugan Subramanian, Eric Flatter, Flatter, Eric, Hervé Moine, Didiot, Marie-Cécile, Moine, Hervé, Jean-Louis Mandel   +9 more
core   +1 more source

Genetic association of FMRP targets with psychiatric disorders [PDF]

, 2020
Genes encoding the mRNA targets of fragile X mental retardation protein (FMRP) are enriched for genetic association with psychiatric disorders. However, many FMRP targets possess functions that are themselves genetically associated with psychiatric ...
Holmans, Peter A., Harwood, Janet, O’Donovan, Michael C., Clifton, Nicholas E., Walters, James T. R., Hall, Jeremy, Rees, Elliott, Pardinas, Antonio. F., Owen, Michael J., Pocklington, Andrew J., Di Florio, Arianna, Kirov, George, Michael C. O’Donovan, Elliott Rees, Antonio F. Pardiñas, James T. R. Walters, Peter A. Holmans, Michael J. Owen, Jeremy Hall, Nicholas E. Clifton, George Kirov, Janet C. Harwood, Arianna Di Florio, Andrew J. Pocklington   +23 more
core   +1 more source

Are UK Research Priorities Aligned? Comparing the Research Priorities of the Down Syndrome, Fragile X Syndrome and Williams Syndrome Communities, With the Research and Funding Landscape

Mind, Brain, and Education, Volume 20, Issue 4, November 2026.
ABSTRACT There is a lack of understanding of how research activity in learning disability compares with community research priorities in the United Kingdom, where an estimated 1.5 million people live with a learning disability. Using Down syndrome (DS), Fragile X syndrome (FXS) and Williams syndrome (WS) as model conditions with learning disability, we
Laura Cristescu, Elizabeth Pellicano, Gaia Scerif, Jo Van Herwegen, Emily K. Farran   +4 more
wiley   +1 more source

Characterization of Fragile X Mental Retardation Protein granules formation and dynamics in Drosophila

Biology Open, 2012
Summary FMRP is an evolutionarily conserved protein that is highly expressed in neurons and its deficiency causes fragile X mental retardation syndrome.
Cristina Gareau, David Martel, Laetitia Coudert, Samia Mellaoui, Rachid Mazroui   +4 more
doaj   +1 more source