Results 21 to 30 of about 47,792 (97)

Mechanisms underlying different onset patterns of focal seizures.

PLoS Computational Biology, 2017
Focal seizures are episodes of pathological brain activity that appear to arise from a localised area of the brain. The onset patterns of focal seizure activity have been studied intensively, and they have largely been distinguished into two types-low ...
Yujiang Wang, Andrew J Trevelyan, Antonio Valentin, Gonzalo Alarcon, Peter N Taylor, Marcus Kaiser   +5 more
doaj   +1 more source

Anticonvulsant effects of cenobamate in chemically and electrically induced seizure models in rodents

Heliyon, 2023
Background: Cenobamate is an antiseizure medication used to treat partial-onset (focal) seizures. It is a molecule with one chiral center and a unique dual mechanism of action: enhancement of fast and slow inactivation of sodium channels with ...
Susan M. Melnick, Yujin Shin, Kelli J. Glenn   +2 more
doaj   +1 more source

Temporal encephalocele: An epileptogenic focus confirmed by direct intracranial electroencephalography

Epilepsy & Behavior Reports, 2023
Several studies have suggested the epileptogenic potential of temporal encephaloceles. However, there is limited literature describing the results of intracranial EEG monitoring for patients with temporal encephaloceles.
Shruti Agashe, Brian N. Lundstrom, Benjamin H. Brinkmann, Elson So, Gregory D. Cascino, Nicholas Gregg, W. Richard Marsh, Madeline Cross, Jamie J. Van Gompel, Kelsey M. Smith   +9 more
doaj   +1 more source

Focal seizures associated with the chapeau de gendarme sign or ictal pouting of insular origin

Epilepsy & Behavior Reports, 2019
We report a teenager with childhood onset focal seizures associated with the chapeau de gendarme sign or ictal pouting of anterior insular lobe origin.
Logan D. Wiwchar, Walter Hader, Anvita Pauranik, Jeffrey T. Joseph, Juan P. Appendino   +4 more
doaj   +1 more source

Seizure semiology and predictors of outcomes in Chinese patients with glutamic acid decarboxylase antibody-associated neurological syndrome

BMC Neurology, 2023
Background In the current study, seizure semiology and potential predictive factors of seizure outcomes in glutamic acid decarboxylase antibody (GAD Ab)-associated neurological syndrome were investigated.
Nan Lin, Lin Bai, Qing Liu, Jianhua Chen, Haitao Ren, Hongzhi Guan, Qiang Lu   +6 more
doaj   +1 more source

Late-Onset Focal Epilepsy: Electroclinical Features and Prognostic Role of Leukoaraiosis

Frontiers in Neurology, 2022
The aim of this study was to describe the electroclinical and prognostic characteristics, and to investigate the role of leukoaraiosis in outpatients with new-onset elderly focal epilepsy aged ≥60 years, referred to a tertiary epilepsy center between ...
Elena Tartara, Elisa Micalizzi, Sofia Scanziani, Elena Ballante, Elena Ballante, Matteo Paoletti, Carlo Andrea Galimberti   +6 more
doaj   +1 more source

Neuroimaging observations in a cohort of elderly manifesting with new onset seizures: Experience from a university hospital

Annals of Indian Academy of Neurology, 2012
Background: The occurrence of epilepsy is higher among elderly patients. The clinical manifestations of seizures, causes of epilepsy, and choice of anti-epileptic drugs (AEDs) are different in elderly people with epilepsy compared to the young.
Sanjib Sinha, Parthasarathy Satishchandra, Balaji Rameshrao Kalband, Rose Dawn Bharath, Kandavel Thennarasu   +4 more
doaj   +1 more source

Status epilepticus during correction of hyponatremia in a patient with Alzheimer’s disease: A case report

SAGE Open Medical Case Reports, 2020
An 83-year-old Japanese man with Alzheimer’s disease was admitted to our hospital for treatment of hyponatremia resulting from water intoxication. During hospitalization, the patient developed focal impaired awareness seizures, focal to bilateral tonic ...
Ken Ichioka, Nobuhiro Akuzawa, Akio Takahashi   +2 more
doaj   +1 more source

Anti-LGI1 encephalitis with initiating symptom of seizures in children

Frontiers in Neuroscience, 2023
BackgroundAnti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis is infrequently reported but more and more recognizable in children. Here we give detailed description of the clinical features and long-term outcome of three cases of childhood onset ...
Yang Wang, Dongqing Zhang, Lili Tong, Lu Yang, Ping Yin, Jun Li, Gefei Lei, Xiaofan Yang, Baomin Li   +8 more
doaj   +1 more source

Gastaut type idiopathic occipital epilepsy

Неврология, нейропсихиатрия, психосоматика, 2015
Idiopathic occipital epilepsy is a rare epileptic syndrome. Its incidence in a Novosibirsk cohort of patients with idiopathic focal epilepsy is 0.9%. Objective: to present a clinical description of new cases of Gastaut syndrome, the types of its course ...
I. V. Volkov, O. K. Volkova
doaj   +1 more source