Results 61 to 70 of about 47,792 (97)

Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis. [PDF]

Drugs, 2022
Lattanzi S, Trinka E, Zaccara G, Striano P, Russo E, Del Giovane C, Silvestrini M, Brigo F.   +7 more
europepmc   +1 more source

Efficacy and Tolerability of Perampanel as Adjunctive Therapy in Chinese Patients With Focal-Onset Seizures: An Observational, Prospective Study. [PDF]

Front Neurol, 2021
Zhang R, Qiao S, Fang X, Wang K, Shi Y, Du Q, Yang T, Liu X.   +7 more
europepmc   +1 more source

Perampanel as First Adjunctive Treatment in Patients with Focal-Onset Seizures in the FAME Study: Post hoc Analyses of Dose-Related Efficacy, Safety and Clinical Factors Associated with Response. [PDF]

J Epilepsy Res, 2022
Kim DW, Kim JH, Lee SK, Lee SA, Lee JW, Kim MY, Seo DW.   +6 more
europepmc   +1 more source

Developing a Conceptual Disease Model of Patient Experiences and Identifying Patient-Reported Clinical Outcome Assessments for Use in Trials of Treatments for Focal Onset Seizures. [PDF]

Neuropsychiatr Dis Treat, 2022
Oberdhan D, Bacci E, Hill JN, Palsgrove A, Hareendran A.   +4 more
europepmc   +1 more source

Efficacy and safety of Brivaracetam as an adjunctive therapy in patients with focal-onset seizures: a phase III, multi-center, randomized, double-blind, placebo-controlled trial. [PDF]

Acta Epileptol
Yu P, Zhao T, Lin W, Han X, Li F, Hong Z.   +5 more
europepmc   +1 more source

Comparison of the effectiveness, safety and tolerability of Perampanel and Levetiracetam as monotherapy in Chinese patients with focal-onset seizures: A single-center, ambispective, open-label, real-world observational study. [PDF]

Epilepsia Open
Ma H, Zhang R, Zhang Y, Xu H, Qu X, Yang Y, Li J, Yang L, Zhou Q, Zhu H.   +9 more
europepmc   +1 more source

Perampanel as First Add-On Therapy in Patients with Focal-Onset Seizures in the FAME Trial: Post hoc Analyses of Efficacy and Safety Related to Maintenance Dose and Background Antiepileptic Drug Therapy. [PDF]

J Epilepsy Res, 2022
Kim JH, Kim DW, Lee SK, Seo DW, Lee JW, Kim MY, Lee SA.   +6 more
europepmc   +1 more source

Efficacy and safety of perampanel as first adjunctive therapy in patients with focal-onset seizures or generalized tonic-clonic seizures in four post-marketing studies across regions. [PDF]

Epilepsia Open
Meletti S, Punia V, Dash A, Gentile AL, Sáinz-Fuertes R, Goldman S, Goldmann T, Patten A, Kumar D, Ngo LY, Steinhoff BJ.   +10 more
europepmc   +1 more source

PAC-FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures. [PDF]

Epilepsia
Anderson LL, Kahlig KM, Barker-Haliski ML, Matthews LG, Toop HD, Hannigan B, French J, White HS, Souza M, Petrou S.   +9 more
europepmc   +1 more source

Real-world use of adjunctive perampanel for focal-onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA). [PDF]

Epilepsia Open
D'Aniello A, Giallonardo AT, Tinuper P, Mecarelli O, Aguglia U, Assenza G, Gambardella A, Canevini MP, Scifo R, Meletti S, De Giorgis V, Bonanni E, Michelucci R, Cerminara C, Romeo A, Vigevano F, Operto FF, Tramacere L, Di Gennaro G, Alfonso Iudice on behalf of the AMPA Study group, Ngo LY, Patten A, Gentile AL, Pecori A, Goldman S.   +24 more
europepmc   +1 more source