Results 141 to 150 of about 113,919,521 (303)

Effects of cyclic tensile strain on the cytoskeletal arrangement and activation of focal adhesion kinase in murine myoblastic precursors [PDF]

, 2012
Mechanical stimulation has been shown capable of modulating cell behaviour. By mechanotransduction cells are able to translate extrinsic stimuli into chemical signals that can affect migration, proliferation, transcription and apoptosis.
Andersen, Jens Isak
core  

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Protective effect and mechanism of citrulline on intestinal injury induced by radiation in mice

He jishu
BackgroundIonizing radiation can cause damage to animal's intestinal tissue. Citrulline is produced in the intestinal epithelial cell and has been proven to possess a protective effect on the gastrointestinal tract.PurposeThis study aims to investigate ...
FENG Jundong, LIU Liang, LIU Wenqian, LI Qian, TIAN Liuxin, HE Chengyu, BO Hongyu, WANG Weitai, YANG Yingqing   +8 more
doaj   +1 more source

Supplementary Table S1 from Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor

, 2009
Supplementary Table S1 from Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal ...
Kazufumi Sakurama (5195891), Yasuhiro Shirakawa (14904657), Yasuko Tomono (447012), Tomoki Yamatsuji (360085), Kazuhiro Noma (14799550), Noriaki Tanaka (8478), Osamu Ohmori (2699242), Munenori Takaoka (447008), Yoshio Naomoto (360090), Nobuyuki Watanabe (3863773), Takayuki Motoki (14973849), Junji Matsuoka (360086), Seiichi Hirota (4424017), Minoru Haisa (10118876), Shinji Hatakeyama (368857)   +14 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Focal Adhesion Kinase: Potential Cancer Inhibitors

, 2012
Focal Adhesion Kinase (FAK) is a non-receptor protein kinase that plays a critical role in cell signaling, and the regulation of many cellular processes.
Globerson, Jeffrey
core  

Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion

, 2017
Dependent on their cellular localization, Protein Kinase D (PKD) enzymes regulate different processes including Golgi transport, cell signaling and response to oxidative stress.
Peter Storz, Nisha Durand, Ligia I. Bastea, Tim Eiseler, Heike Döppler   +4 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Focal Adhesion Kinase 1 [PDF]

, 2020
openaire   +1 more source