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Identification of potential focal adhesion kinase (FAK) inhibitors: a molecular modeling approach
Journal of Biomolecular Structure and DynamicsFocal adhesion kinase (FAK) is an enzyme of paramount importance as it is involved in several critical roles, which are linked to proliferation of cancer cells. FAK is quintessential for cancer cell mitigation, adhesion and survival, downregulation of which interferes with the growth of cancer cells.
Sahaya Nadar +2 more
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Focal Adhesion Kinase Inhibitors in the Treatment of Solid Tumors: Preclinical and Clinical Evidence
Drug Discovery Today, 2022Martín J Lavecchia +1 more
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Focal Adhesion Kinase: In Command and Control of Cell Motility
Nature Reviews Molecular Cell Biology, 2005David Schlaepfer
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