Results 201 to 210 of about 1,278,750 (244)

The Role of Focal Adhesion Kinase (FAK) in Contact Inhibition.

open access: yesCellular & molecular biology letters
Joanna, Miloszewska   +3 more
openaire   +1 more source

Regulation of Adhesion Dynamics by Calpain-Mediated Proteolysis of Focal Adhesion Kinase (FAK) [PDF]

open access: yesJournal of Biological Chemistry, 2010
The coordinated and dynamic regulation of adhesions is required for cell migration. We demonstrated previously that limited proteolysis of talin1 by the calcium-dependent protease calpain 2 plays a critical role in adhesion disassembly in fibroblasts (Franco, S. J., Rodgers, M. A., Perrin, B. J., Han, J., Bennin, D. A., Critchley, D.
Keefe T Chan, Anna Huttenlocher
exaly   +5 more sources

Cleavage of focal adhesion kinase (FAK) is essential in adipocyte differentiation

Biochemical and Biophysical Research Communications, 2007
During adipocyte differentiation, the cells experience dramatic alterations in morphology, motility and cell-ECM contact. Focal adhesion kinase (pp125FAK), a widely expressed non-receptor tyrosine kinase in integrin signaling, has been reported to participate in these events in various cells.
Jing-Jing, Li, Dong, Xie
openaire   +2 more sources

Concentration of pp125 focal adhesion kinase (FAK) at the myotendinous junction

Journal of Cell Science, 1994
ABSTRACT Focal adhesion kinase is a recently characterized tyrosine kinase that is concentrated at focal contacts in cultured cells. It is thought to play an important role in the the reg- ulation of the integrin-based signal transduction mechanism involved in the assembly of this membrane spe- cialization. In this study, we examined the
Baker, L.P.   +2 more
openaire   +2 more sources

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