The FASEB Journal, Volume 40, Issue 6, 31 March 2026.This graphical abstract illustrates an integrative analysis of single‐cell RNA‐seq data in CKD. DEGs were subsequently identified as candidate genes via Mendelian randomization analysis and combined with MAGMA analysis, ITCH was identified as a key gene.
Xia Zhang +7 more
wiley +1 more source
Idiopathic focal segmental glomerulosclerosis and HLA antigens
Brazilian Journal of Medical and Biological Research, 1998 The objective of the present study was to investigate a possible association between HLA class II antigens and idiopathic focal segmental glomerulosclerosis (FSGS).
M. Gerbase-DeLima +5 more
doaj +1 more source
Contribution of Renal and Non‐Renal Clearance on Increased Total Clearance of Adalimumab in Glomerular Disease [PDF]
, 2013 The contribution of renal and non‐renal clearance toward targeted concentrations and/or effects of therapeutic proteins in nephrotic patients are unknown.
Akilesh +24 more
core +1 more source
Renal and Cardiovascular Morbidities Associated with APOL1 Status among African-American and Non-African-American Children with Focal Segmental Glomerulosclerosis [PDF]
, 2016 Background and objectives: African American (AA) children with focal segmental glomerulosclerosis (FSGS) have later onset disease that progresses more rapidly than in non-AA children.
Bradley A. Warady +11 more
core +2 more sources
Focal Segmental Glomerulosclerosis: A Single Center Experience
Haseki Tıp Bülteni, 2016 Aim: Focal segmental glomerulosclerosis (FSGS) is one of the most common glomerulonephritis (GNP) worldwide. Despite treatment, it may progress to end-stage renal disease. In the present study, we compared clinical and histopathological data on FSGS with
Yavuz Ayar +14 more
doaj +1 more source
Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]
, 2012 Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
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Focal Segmental Glomerulosclerosis: Histopathology Discussion
European Medical Journal Nephrology, 2022 Brian Mark Churchill +3 more
doaj +1 more source
Identification of a novel regulatory mechanism for the disease associated protein, uPAR [PDF]
, 2014 Expression quantitative trait loci (eQTLs), as determined through a series of statistical association studies collectively known as genome-wide association (GWA) studies, have provided us with a hypothesis free approach for the investigation into ...
Hall, Ian P. +2 more
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Tacrolimus rescue therapy for renal allograft rejection - Five-year experience [PDF]
, 1997 Over the 5 year period from 7/14/1989 until 5/24/1994, we have attempted graft salvage with tacrolimus conversion in a total of 169 patients (median age 33 years, range 2-75 years) with ongoing rejection on baseline CsA immunosuppression after failure of
Demetris, AJ +12 more
core +1 more source
Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]
, 2018 The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Asfahani, R +10 more
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