Results 61 to 70 of about 21,067 (213)

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, EarlyView.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR‐217/SIRT1/Nrf2 pathway

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
These findings indicate that urinary exosomal miR‐217 promotes podocyte ferroptosis and DKD progression via suppression of the SIRT1/Nrf2 pathway, suggesting a potential therapeutic target for DKD. Abstract Urinary exosomal microRNAs (miRNAs) mediate intercellular communication in diabetic kidney disease (DKD), a leading contributor to end‐stage renal ...
Xin Du, Yubo Jiang, Hongbin Guo, Haiying Zhang, Shaoqing Wang, Hao Deng, Xinyi Huang, Xiu Li   +7 more
wiley   +1 more source

Schistosomal glomerulopathy and changes in the distribution of histological patterns of glomerular diseases in Bahia, Brazil

Memorias do Instituto Oswaldo Cruz, 2011
Distinct patterns of glomerular lesions, including membranoproliferative glomerulonephritis and focal segmental glomerulosclerosis, are associated with infection by Schistosoma mansoni or Schistosoma japonicum.
Washington Luis Conrado dos-Santos, Glória Maria Maranhão Sweet, Marília Bahiense-Oliveira, Paulo Novis Rocha   +3 more
doaj   +1 more source

Pemphigus vulgaris and focal segmental glomerulosclerosis (FSGS): First reported case and a review of the literature

Clinical Case Reports, 2023
Key Clinical Message There may be a connection between pemphigus vulgaris and nephrotic syndrome, as evidenced by the occurrence of focal segmental glomerulosclerosis in our pemphigus vulgaris patient and reviewing relevant literature.
Afsaneh Sadeghzadeh‐Bazargan, Atefeh Amouzegar, Maryam Abolhasani, Abbas Dehghani, Azadeh Goodarzi, Seyyedeh Tahereh Rahimi   +5 more
doaj   +1 more source

Clinical characteristics of patients with secondary focal segmental glomerulosclerosis (FSGS).

, 2014
Clinical characteristics of patients with secondary focal segmental glomerulosclerosis (FSGS).
Philip A. Marsden (252499), Ian W. Gibson (537851), Kim A. Connelly (204407), Darren J. Kelly (252497), Manish M. Sood (537850), Andrew Advani (204406), Kerri Thai (252495), Li-Hao Chen (537849), Suzanne L. Advani (204410), M. Golam Kabir (204417), Darren A. Yuen (204408), Richard E. Gilbert (204424)   +11 more
core   +1 more source

Focal and Segmental Glomerulosclerosis and Membranous Nephropathy overlapping in a patient with Nephrotic Syndrome: a case report

Brazilian Journal of Nephrology, 2019
Introduction: Some cases of membranous nephropathy (MGN) present focal segmental glomerulosclerosis (FSGS) typically associated with disease progression. However, we report a case of a patient who seemed to have MGN and FSGS, both primary.
Crislaine Aparecida da Silva, Fabiano Bichuette Custódio, Maria Luíza Gonçalves dos Reis Monteiro, Stanley de Almeida Araújo, Liliane Silvano Araújo, Rosana Rosa Miranda Côrrea, Marlene Antônia dos Reis, Juliana Reis Machado   +7 more
doaj   +1 more source

A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects

JCI Insight, 2022
The LAMA5 gene encodes laminin α5, an indispensable component of glomerular basement membrane and other types of basement membrane. A homozygous pathological variant in LAMA5 is known to cause a systemic developmental syndrome including glomerulopathy ...
Jun-Ya Kaimori, Yamato Kikkawa, Daisuke Motooka, Tomoko Namba-Hamano, Ayako Takuwa, Atsuko Okazaki, Kaori Kobayashi, Arisa Tanigawa, Yuko Kotani, Yoshihiro Uno, Kazuto Yoshimi, Koki Hattori, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Tatsufumi Oka, Yusuke Sakaguchi, Tomoji Mashimo, Kiyotoshi Sekiguchi, Akihiro Nakaya, Motoyoshi Nomizu, Yoshitaka Isaka   +21 more
doaj   +1 more source

POEMS syndrome, calciphylaxis and focal segmental glomerulosclerosis - VEGF as a possible link.

, 2014
Polyneuropathy organomegaly endocrinopathy M-protein skin changes (POEMS) syndrome is a rare cause of polyneuropathy. Calciphylaxis, a severe disease leading to necrotic ulcers of the skin, is associated with POEMS syndrome and also with renal disease ...
Heck, Dorothee;Mergen, Miriam;Ganner, Athina;Pelisek, Jaroslav;Mader, Irina;Weiller, Cornelius;Niesen, Wolf-Dirk
core   +2 more sources

Biomarkers for Early Detection of Diabetic Kidney Disease in Pediatric and Adolescent Populations: A Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Diabetic nephropathy is among the most critical long‐term complications linked to diabetes, substantially influencing both morbidity and mortality. Although it was once largely associated with adults, diabetic kidney disease (DKD) has now become a leading source of kidney complications among children worldwide.
Iran Malekzadeh, Narges Falsafi, Mohammad Nazemi, Hanie Taherkhani, Mahboube Bahroudi, Asim Abbas, Mastaneh Moghtaderi   +6 more
wiley   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source