Results 31 to 40 of about 1,404,808 (156)
, 2004 For folate-receptor-targeted. anti-cancer therapy, doxorubicin aggregates in a nano-scale size were produced employing doxorubicin-polyethylene glycol-folate (DOX-PEG-FOL) conjugate. Doxorubicin and folate were respectively conjugated to alpha- and omega-
Park, TG, Yoo, HS
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Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity? [PDF]
, 2011 One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal cell damage.
M. Lluïsa Sagristá +15 more
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Folate receptors detection based on the immobilization of folic acid onto Ti−W oxides thin film
Biosensors and Bioelectronics: XThe overexpression of folate receptors on cell surfaces is associated with abnormalities linked to epithelial cancers. This study reports on a capacitive biosensor that employs folic acid as a recognition molecule for the biosensing of folate receptors ...
Linda Bertel +3 more
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Pteridines, 2015 Folate receptors and transporters as well as folate enzymes play an essential role in human disease and form important targets for the treatment of immune diseases and cancer.
Jansen Gerrit, Peters Godefridus J.
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Effects of Polyethylene Glycol Spacer Length and Ligand Density on Folate Receptor Targeting of Liposomal Doxorubicin In Vitro [PDF]
, 2011 The folate receptor is an attractive target for selective tumor delivery of liposomal doxorubicin (DXR) because it is abundantly expressed in a large percentage of tumors.
Kumi Kawano, Yoshie Maitani
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Folate receptor: a potential target in ovarian cancer
Pteridines, 2015 Ovarian cancer is the most frequent cause of gynecological cancer-related death. Unfortunately, many patients are diagnosed at an advanced stage and have a poor prognosis. The standard treatment for advanced disease involves maximal cytoreductive surgery
Bartouskova Marie +2 more
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, 2011 The aim of the present study was to prepare 99mTc-folate- glucaric acid and investigate the radiopharmaceutical potential for tumors imaging that over express folate receptor.
Onursal M., Lambrecht F.Y., Ozgur A.
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Conjugation of Folate via Gelonin Carbohydrate Residues Retains Ribosomal-inactivating Properties of the Toxin and Permits Targeting to Folate Receptor Positive Cells [PDF]
, 2001 Conjugation of folate to proteins permits receptor-mediated endocytosis via the folate receptor (FR) and delivery of the conjugate into the cytoplasm of cells.
Atkinson, Sarah F. +12 more
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Internalization of methotrexate conjugates by folate receptor-α [PDF]
, 2018 The folate antagonist methotrexate is a cytotoxic drug used in the treatment of several cancer types. Methotrexate entry into the cell is mediated by two main transport systems: the reduced folate carrier and membrane-associated folate receptors.
Azóia, Nuno G. +18 more
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Measurement of endosome pH following folate receptor-mediated endocytosis
, 1996 Free folic acid is believed to enter some cells by folate receptor-mediated endocytosis at membrane invaginations termed caveolae. Folate conjugated macromolecules also enter cells by folate receptor-mediated endocytosis, but their site of entry has ...
Lee, Robert J. +2 more
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