Results 21 to 30 of about 1,404,808 (156)

Folate bioavailability [PDF]

, 2009
An inadequate folate status is associated with increased risk of anaemia and neural tube defects. In many countries a folate intake below recommendations has been reported for women in childbearing age.
Öhrvik, Veronica
core   +1 more source

Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1 [PDF]

, 2010
Background Using a functional genomics approach we addressed the impact of folate overproduction on metabolite formation and gene expression in Lactobacillus plantarum WCFS1.
Vos, W.M., de, Willem M de Vos, Smid Eddy J, Eddy J Smid, Smid, E.J., Faijes Magda, Vos, R.C.H., de, Mars Astrid E, de Vos, R.C.H.., Klaus, M.J., Molenaar, D., Mars, A.E., Sebastian MJ Klaus, Molenaar, D.; id_orcid, Hanson, A.D., Wegkamp Arno, Douwe Molenaar, Astrid E Mars, Wegkamp, H.B.A., Molenaar Douwe, Klaus, S.M.J., Hanson Andrew D, Wegkamp, A., Magda Faijes, Faijes, M., Vos, W.M., Arno Wegkamp, de Vos Willem M, de Vos Ric CH, Andrew D Hanson, Klaus Sebastian MJ, Ric CH de Vos   +31 more
core   +1 more source

Development of Folate-Functionalized PEGylated Zein Nanoparticles for Ligand-Directed Delivery of Paclitaxel

Pharmaceutics, 2019
In this study, we investigated the active targeted delivery of a hydrophobic drug, paclitaxel (PTX), via receptor-mediated endocytosis by folate receptors expressed on cancer cells using a protein-based nanoparticle system.
Zar Chi Soe, Wenquan Ou, Milan Gautam, Kishwor Poudel, Bo Kyun Kim, Le Minh Pham, Cao Dai Phung, Jee-Heon Jeong, Sung Giu Jin, Han-Gon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim   +12 more
doaj   +1 more source

Pharmacoresistant Epilepsy in Childhood: Think of the Cerebral Folate Deficiency, a Treatable Disease

Brain Sciences, 2020
Cerebral folate deficiency (CFD) is a neurological disorder characterized by low levels of 5-methyltetrahydrofolate (5-MTHF) in the cerebrospinal fluid (CSF). The prevalence of this autosomal recessive disorder is estimated to be A, p.Cys66Tyr).
Sarah Mafi, Cécile Laroche-Raynaud, Pauline Chazelas, Anne-Sophie Lia, Paco Derouault, Franck Sturtz, Yasser Baaj, Rachel Froget, Marlène Rio, Jean-François Benoist, François Poumeaud, Frédéric Favreau, Pierre-Antoine Faye   +12 more
doaj   +1 more source

Cerebral Folate Deficiency & Receptor Mutations

Pediatric Neurology Briefs, 2012
Researchers at University Medical Centre Gottingen, other centers in Germany, and Helsinki University Central Hospital, Finland screened 72 children with low 5-methyltetrahydrofolate (5-MTHF) concentrations in the CSF who developed neurological ...
J Gordon Millichap
doaj   +1 more source

Ischemia-Reperfusion Injury Reduces Kidney Folate Transporter Expression and Plasma Folate Levels

Frontiers in Immunology, 2021
Acute or chronic kidney disease can cause micronutrient deficiency. Patients with end-stage renal disease, kidney transplantation or on dialysis have reduced circulating levels of folate, an essential B vitamin.
Cheng Yang, Cheng Yang, Charith U. B. Wijerathne, Charith U. B. Wijerathne, Guo-wei Tu, Connie W. H. Woo, Yaw L. Siow, Yaw L. Siow, Yaw L. Siow, Susara Madduma Hewage, Susara Madduma Hewage, Kathy K. W. Au-Yeung, Kathy K. W. Au-Yeung, Tongyu Zhu, Tongyu Zhu, Karmin O, Karmin O, Karmin O   +17 more
doaj   +1 more source

Synthesis of [^99mTc]DTPA-Folate and Its Evaluation as a Folate-Receptor-Targeted Radiopharmaceutical

, 2016
A DTPA−folate conjugate was radiolabeled with 99mTc by stannous chloride reduction of [99mTc]sodium pertechnetate in an aqueous solution of DTPA−folate.
David Hubers (2944776), Philip S. Low (371711), Carla J. Mathias (2682121), Mark A. Green (1292190)   +3 more
core   +1 more source

Potential Use of Folate-polyethylene glycol (PEG)-Appended Dendrimer (G3) Conjugate with alpha-Cyclodextrin as DNA Carriers to Tumor Cells [PDF]

, 2011
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with alpha-cyclodextrin (alpha-CyD) having an average degree of substitution of 2.4 of alpha-CyD (alpha-CDE) provided remarkable aspects as novel ...
Masayo Arizono, Fumitoshi Hirayama, Hidetoshi Arima, Haruna Ikeda, Tomoko Takeuchi, Kaneto Uekama, Taishi Higashi, Ayumi Yoshimitsu, Kenjiro Hattori, Keiichi Motoyama   +9 more
core  

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Folate Receptor-Targeted and GSH-Responsive Carboxymethyl Chitosan Nanoparticles Containing Covalently Entrapped 6-Mercaptopurine for Enhanced Intracellular Drug Delivery in Leukemia

Marine Drugs, 2018
For enhanced intracellular accumulation of 6-mercaptopurine (6-MP) in leukemia, a folate receptor-targeted and glutathione (GSH)-responsive polymeric prodrug nanoparticle was made.
Xuan Wei, Jianhong Liao, Zahra Davoudi, Hua Zheng, Jingru Chen, Dan Li, Xiong Xiong, Yihua Yin, Xiuxiang Yu, Jinghui Xiong, Qun Wang   +10 more
doaj   +1 more source