Results 1 to 10 of about 1,404,808 (156)
Folate Receptor Alpha Autoantibodies in Vector-Borne Disease Populations [PDF]
DiseasesBackground: Vector-borne diseases (VBDs) caused by Borrelia spp., Bartonella spp., and Babesia spp. are associated with neuropsychiatric morbidity. Cerebral folate deficiency (CFD), primarily caused by folate receptor-α autoantibodies (FRAAs) impairing ...
Lindsey Wells +3 more
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Progress of Folic Acid-Folate Receptor as Drug Carriers in Targeted Drug Delivery System [PDF]
SHS Web of Conferences, 2022 Targeted drug delivery system is an effective method for the diagnosis and treatment of cancer, it has received much attention because of its low side effects and therapeutic efficacy. Folic acid receptor is highly expressed on the surface of most cancer
Zhang Zhanpeng
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A Bibliometric analysis of folate receptor research
BMC Cancer, 2020 Background The objective of this study was to conduct a bibliometric analysis of the entire field of folate receptor research. Folate receptor is expressed on a wide variety of cancers and certain immune cells.
Cari A. Didion, Walter A. Henne
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Dual membrane receptor degradation via folate receptor targeting chimera [PDF]
Nature CommunicationsCancer drug resistance poses a significant challenge in oncology, often driven by intricate cross-talk among membrane-bound receptors that compromise mono-targeted therapies.
Zhen Wang +15 more
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Biomolecules, 2022 Despite continuous advances, anticancer therapy still faces several technical hurdles, such as selectivity on cellular and subcellular targets of therapeutics.
Davide Cardella +3 more
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Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors
Biomolecules, 2020 This report presents the synthesis and folate receptor target-specificity of amino-functionalized polyacrylamide nanoparticles (AFPAA NPs) for near-infrared (NIR) fluorescence imaging of cancer. For the synthesis of desired nano-constructs, the AFPAA NPs
Aimee J. Marko +7 more
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Heliyon, 2021 Cancer is one of the main causes of human mortality worldwide and novel chemotherapeutics are required due to the limitations of conventional cancer therapies.
Ali Razaghi +4 more
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Evaluation of Folate-Functionalized Nanoparticle Drug Delivery Systems—Effectiveness and Concerns
Biomedicines, 2023 Targeting folate receptors is a potential solution to low tumor selectivity concerning conventional chemotherapeutics. Apart from antibody–drug conjugates, folate-functionalized nanoparticle drug delivery systems are interesting to be explored due to ...
Muhammad Aiman Irfan Ibrahim +3 more
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Molecules, 2021 In order to seek novel technetium-99m folate receptor-targeting agents, two folate derivatives (CN5FA and CNPFA) were synthesized and radiolabeled to obtain [99mTc]Tc-CN5FA and [99mTc]Tc-CNPFA complexes, which exhibited high radiochemical purity (>95 ...
Junhong Feng +4 more
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Vintafolide: a novel targeted therapy for the treatment of folate receptor expressing tumors
Therapeutic Advances in Medical Oncology, 2015 Despite advances in the development of molecularly targeted therapies, limited improvements in overall survival have been noted among many cancer patients with solid tumors, primarily due to development of drug resistance.
Ignace Vergote, Christopher P. Leamon
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