Results 11 to 20 of about 1,404,808 (156)

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

Beilstein Journal of Nanotechnology
Theragnostic platforms, which integrate therapeutic and diagnostic capabilities, have gained significant interest in drug research because of to their potential advantages.
Thi Ngoc Han Pham, Phuong-Thao Dang-Luong, Hong-Phuc Nguyen, Loc Le-Tuan, Xuan Thang Cao, Thanh-Danh Nguyen, Vy Tran Anh, Hieu Vu_Quang   +7 more
doaj   +2 more sources

Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism

International Journal of Nanomedicine, 2011
Hong Yang1,*, Changchun Lou1,*, Mingming Xu1, Chunhui Wu1, Hirokazu Miyoshi2, Yiyao Liu1,31Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s ...
Yang H, Lou C, Xu M, Wu C, Miyoshi H, Liu Y   +5 more
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Expression of folate receptors in nasopharyngeal and laryngeal carcinoma and folate receptor-mediated endocytosis by molecular targeted nanomedicine

International Journal of Nanomedicine, 2013
M Xie, H Zhang, Y Xu, T Liu, S Chen, J Wang, T ZhangDepartment of Otorhinolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of ChinaAbstract: Immunohistochemistry and an immunofluorescence
Xie M, Zhang H, Xu Y, Liu T, Chen S, Wang J, Zhang T   +6 more
doaj   +1 more source

Folate Receptor Targeted Alpha-Therapy Using Terbium-149 [PDF]

Pharmaceuticals, 2014
Terbium-149 is among the most interesting therapeutic nuclides for medical applications. It decays by emission of short-range α-particles (Eα = 3.967 MeV) with a half-life of 4.12 h. The goal of this study was to investigate the anticancer efficacy of a
Cristina Müller, Josefine Reber, Stephanie Haller, Holger Dorrer, Ulli Köster, Karl Johnston, Konstantin Zhernosekov, Andreas Türler, Roger Schibli   +8 more
doaj   +3 more sources

Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation. [PDF]

, 2013
Folate status, as reflected by red blood cell (RCF) and plasma folates (PF), is related to health and disease risk. Folate degradation products para-aminobenzoylglutamate (pABG) and para-acetamidobenzoylglutamate (apABG) in 24 hour urine have recently ...
Berthold Koletzko (144194), Rauh-Pfeiffer Astrid, Demmelmair Hans, Astrid Rauh-Pfeiffer, Weith, Thea, Berthold Koletzko, Weith Thea, Marola van Lipzig (282250), Rauh-Pfeiffer, Astrid, Mareile Niesser, Rauh-Pfeiffer, Astrid A. M., Wolfgang Peissner (282252), Niesser Mareile, Vaes Wouter, Peissner Wolfgang, Moretti, Diego, Hans Demmelmair (212025), Demmelmair, Hans, Diego Moretti, Vaes, Wouter, Diego Moretti (282248), Wouter Vaes (282251), van Lipzig Marola, Koletzko Berthold, van Lipzig, Marola, Astrid Rauh-Pfeiffer (282249), Hans Demmelmair, Thea Weith, Wolfgang Peissner, Moretti Diego, Koletzko, Berthold, Marola van Lipzig, Thea Weith (282247), Peissner, Wolfgang, Wouter Vaes, Niesser, Mareile, Mareile Niesser (282246)   +36 more
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Redox-Sensitive and Folate-Receptor-Mediated Targeting of Cervical Cancer Cells for Photodynamic Therapy Using Nanophotosensitizers Composed of Chlorin e6-Conjugated β-Cyclodextrin via Diselenide Linkage

Cells, 2021
The aim of this study was to fabricate a reactive oxygen species (ROS)-sensitive and folate-receptor-targeted nanophotosensitizer for the efficient photodynamic therapy (PDT) of cervical carcinoma cells.
Howard Kim, Mi Woon Kim, Young-IL Jeong, Hoe Saeng Yang   +3 more
doaj   +1 more source

Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation [PDF]

, 2014
Scope Investigate the influence of low-folate supply during pregnancy and lactation on obesity and markers of the metabolic syndrome in offspring, and how provision of a high-fat diet post weaning may exacerbate the resultant phenotype.
Sabine A. S. Langie, Caroline Manus, Jill A. McKay, Mckay, Jill A., Maxwell, Ross J., Manus, Caroline, Dianne Ford, Maxwell, Ross, Long Xie, Ross J. Maxwell, Langie, Sabine A.S.; id_orcid, Xie, Long, Mathers, John C., McKay, Jill, Langie, Sabine, Ford, Dianne, John C. Mathers   +16 more
core   +1 more source

Targeted Thiazole Orange Derivative with Folate: Synthesis, Fluorescence and in Vivo Fluorescence Imaging

Molecules, 2010
A Thiazole Orange conjugated with folate derivative was synthesized in two steps. Firstly, folate was coupled with 1-(3-aminopropyl)-4-methylquinolinium bromide to afford folate-methylquinolinium bromide, which then reacted with benzothiazolium to obtain
Qingyang Meng, Baolian Zhang, Yiqi Wang, Xuening Fei, Yingchun Gu   +4 more
doaj   +1 more source

18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease—A Proof-of-Concept Study

Frontiers in Immunology, 2019
Background: Interstitial lung disease (ILD) is a common and severe complication in rheumatic diseases. Folate receptor-β is expressed on activated, but not resting macrophages which play a key role in dysregulated tissue repair including ILD.
Janine Schniering, Martina Benešová, Martina Benešová, Matthias Brunner, Stephanie Haller, Susan Cohrs, Thomas Frauenfelder, Bart Vrugt, Carol Feghali-Bostwick, Roger Schibli, Roger Schibli, Oliver Distler, Cristina Müller, Cristina Müller, Britta Maurer   +14 more
doaj   +1 more source

EEG and Seizure Manifestations of Cerebral Folate Deficiency

Pediatric Neurology Briefs, 2012
Researchers from Duke University Medical Center, Durham, NC report the EEG and seizure manifestations in 2 patients with folate receptor autoimmune antibody-mediated primary cerebral folate deficiency.
J Gordon Millichap
doaj   +1 more source