Results 111 to 120 of about 457,931 (292)

Dietary Intake of Natural Sources of Docosahexaenoic Acid and Folate in Pregnant Women of Three European Cohorts [PDF]

open access: yes, 2008
Background: Folic acid plays a fundamental role in cell division and differentiation. Docosahexaenoic acid (DHA) has been associated with infantile neurological and cognitive development.
Campoy, C.   +6 more
core   +1 more source

Intestinal folate transport: iventification of a cDNA involved in folate transport and the functional expression and distribution of its mRMA

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Although the mechanism of folate intestinal transport has been the subject of intensive studies, very little is known about the molecular identity of the transport system(s) involved. In this investigation, we screened a mouse intestinal cDNA library using as probe the cDNA clone of a reduced folate carrier (RFC1) of mouse leukemia L1210 cells, and ...
Said, Hamid M.   +4 more
openaire   +2 more sources

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

C1-Pathways in Methyloversatilis universalis FAM5: Genome Wide Gene Expression and Mutagenesis Studies

open access: yesMicroorganisms, 2015
Methyloversatilis universalis FAM5 utilizes single carbon compounds such as methanol or methylamine as a sole source of carbon and energy. Expression profiling reveals distinct sets of genes altered during growth on methylamine vs methanol.
Nathan M. Good   +4 more
doaj   +1 more source

When Is a Heme Transporter Not a Heme Transporter? When It's a Folate Transporter [PDF]

open access: yesCell Metabolism, 2007
Essential nutrients enter the body through a variety of specific transporter molecules expressed in the intestinal epithelium. A recent paper by elegantly demonstrates that one of these transporters, previously thought to carry heme, is in fact an important folate transporter.
openaire   +2 more sources

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Dissecting the genetic control of folate homeostasis in plants

open access: yes, 2008
Because of its central role in purine and thymidylate biosynthesis, folate-mediated one-carbon metabolism has been the target of many anticancer drug therapies.
Gonzalez-Jorge, Sabrina
core  

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang   +7 more
wiley   +1 more source

Impact of cold plasma pretreatment and hybrid infrared—hot air drying on bioactive compounds, antioxidant activity, colorimetric attributes, and texture of red beet

open access: yesJSFA reports, EarlyView.
Abstract Background Drying is essential for food preservation, yet conventional methods often compromise product quality. This study investigated the effects of cold plasma pretreatment time (0, 15, and 30 s) and an intermittent infrared‐hot air hybrid dryer (300, 600, and 900 W; pulse ratios 1 and 2) on the functional and quality attributes of dried ...
Farhoud Manafi   +3 more
wiley   +1 more source

Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats

open access: yes, 2011
Folates, an essential component (important B vitamin) in the human diet, are involved in many metabolic pathways, mainly in carbon transfer reactions such as purine and pyrimidine biosynthesis and amino acid interconversions.
Krishan Lal Khanduja   +3 more
core   +1 more source

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