Results 181 to 190 of about 391,837 (318)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Stigleman Manufacturing Company, Stack of Wooden Folding Chairs

open access: yes, 1900
This display shows how well the wooden folding chairs go together when they are ...
Cephas M. Huddleston
core  

Calmodulin assists during co-translational folding of the K<sub>V</sub>7.2 channel calcium responsive domain. [PDF]

open access: yesProtein Sci
Muguruza-Montero A   +10 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Stigleman Manufacturing Company, Oak Folding Chair

open access: yes, 1900
One oak folding chair, closed and displaying the metal supports under the ...
Cephas M. Huddleston   +1 more
core  

Folding $$\pi $$

open access: yes
It is well known that the set of origami constructible numbers is larger than the classical straight-edge and compass constructible numbers. However, the Huzita-Justin-Hatori origami constructible numbers remain algebraic so that the transcendental number $\pi$ can only be approximated using a finite number of straight line folds.
openaire   +2 more sources

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