Results 21 to 30 of about 11,732 (171)

Prognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant FOLFIRINOX

Gut and Liver, 2021
Background/Aims: There has been growing evidence on the utility of neoadjuvant FOLFIRINOX in borderline resectable (BR) or locally advanced (LA) pancreatic cancer.
Young Hoon Choi, Sang Hyub Lee, Min Su You, Bang Sup Shin, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim, Wooil Kwon, Jin-Young Jang, Sun-Whe Kim   +9 more
doaj   +1 more source

Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies

Gut and Liver, 2022
Background/Aims: Three-dimensional cultures of human pancreatic cancer tissue also known as “organoids” have largely been developed from surgical specimens.
Jee Hyung Lee, Haeryoung Kim, Sang Hyub Lee, Ja-Lok Ku, Jung Won Chun, Ha Young Seo, Soon Chan Kim, Woo Hyun Paik, Ji Kon Ryu, Sang Kook Lee, Andrew M. Lowy, Yong-Tae Kim   +11 more
doaj   +1 more source

Dendritic cell-based vaccination: powerful resources of immature dendritic cells against pancreatic adenocarcinoma

OncoImmunology, 2018
Pancreatic adenocarcinoma (PAC) has a poor prognosis. One treatment approach, investigated here, is to reinforce antitumor immunity. Dendritic cells (DCs) are essential for the development and regulation of adaptive host immune responses against tumors ...
Aurélie Collignon, Françoise Silvy, Stéphane Robert, Malika Trad, Sébastien Germain, Jérémy Nigri, Frédéric André, Véronique Rigot, Richard Tomasini, Bernard Bonnotte, Dominique Lombardo, Eric Mas, Evelyne Beraud   +12 more
doaj   +1 more source

Hepatic Arterial Infusion Chemotherapy With Folfirinox or Oxaliplatin Alone in Metastatic Colorectal Cancer

Frontiers in Medicine, 2022
BackgroundHepatic arterial infusion (HAI) of chemotherapy is an option for the treatment of patients with liver metastases from colorectal cancer (LMCRC).
Violaine Randrian, Simon Pernot, Baptiste Sionneau, Denis Smith, Annie Lim, Yann Touchefeu, Claire Gallois, Anthony Turpin, Sahir Javed, Rosine Guimbaud, Pascale Rivera, Mehdi Karoui, Edouard Auclin, Edouard Auclin, Julien Taieb   +14 more
doaj   +1 more source

[Comment] Brazil-TNT : a randomized phase 2 trial of neoadjuvant chemoradiation followed by FOLFIRINOX versus chemoradiation for stage Ⅱ/Ⅲ rectal cancer

结直肠肛门外科
[Background] Neoadjuvant radiation and oxaliplatin-based systemic therapy (total neoadjuvant therapy, TNT) have been shown to increase response and organ-preservation rates in localized rectal cancer.
Li Laiyuan, Yang Xiongfei
doaj   +1 more source

LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer

Frontiers in Oncology, 2021
Pancreatic cancer (PC) is one of the deadliest gastrointestinal cancers, accounting for the fourth highest number of cancer-related fatalities. Increasing data suggests that mesenchymal stem cells (MSCs) might influence the drug resistance of GC cells in
Dongfeng Cheng, Juanjuan Fan, Kai Qin, Yiran Zhou, Jingrui Yang, Yang Ma, Minmin Shi, Minmin Shi, Jiabin Jin   +8 more
doaj   +1 more source

Treatment patterns and cost estimations of systemic chemotherapy for pancreatic cancer in Japan: A retrospective database study

Cancer Medicine, 2023
Background This study aimed to clarify the treatment patterns of pancreatic cancer patients receiving systemic chemotherapy in Japan and to estimate the direct medical costs in actual practice.
Yuki Takumoto, Ryotaro Shibahara, Hajime Asami, Manabu Akazawa   +3 more
doaj   +1 more source

Added Value of Radiotherapy Following Neoadjuvant FOLFIRINOX for Resectable and Borderline Resectable Pancreatic Cancer: A Systematic Review and Meta-Analysis [PDF]

, 2021
Background: The added value of radiotherapy following neoadjuvant FOLFIRINOX chemotherapy in patients with resectable or borderline resectable pancreatic cancer ((B)RPC) is unclear.
van Eijck, Casper H. J., Groot Koerkamp, Bas; id_orcid, van Dam, Jacob L., Besselink, Marc G., van Eijck, Casper H J, van Santvoort, Hjalmar J., Wilmink, Johanna W., Wei, Alice C., Janssen, Quisette P., de Wilde, Roeland F., Homs, Marjolein Y V, de Wilde, Roeland F, Nuyttens, Joost J.M.E., Wilmink, Johanna W, Homs, Marjolein Y. V., Kivits, Isabelle G., van Dam, Jacob L, Kivits, Isabelle G, Besselink, Marc G, Wei, Alice C, Nuyttens, Joost J M E, van Eijck, Casper H.J., Groot Koerkamp, Bas, Nuyttens, Joost J. M. E., van Santvoort, Hjalmar J, Janssen, Quisette P, Qi, Hongchao, Homs, Marjolein Y.V., van Tienhoven, Geertjan   +28 more
core   +2 more sources

Diverse avenues of research support the transmethylation theory of psychosis: implications for neuroprotection

Exploration of Neuroprotective Therapy
Transmethylation in the context of psychiatry has historically referred to the enzymatic transfer of a methyl group from one biochemical to another, whose resulting function can change so dramatically that a biochemical like tryptamine, for example, is ...
Christine L. Miller
doaj   +1 more source

Excellent Response to Olaparib in a Patient with Metastatic Pancreatic Adenocarcinoma with Germline BRCA1 Mutation after Progression on FOLFIRINOX: Case Report and Literature Review

Case Reports in Oncology, 2020
Metastatic pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. Until recently, cytotoxic chemotherapy was the only treatment option. Currently, there are subgroups of patients with PDAC either with somatic or germline mutations who are ...
Jefferson Rios Pimenta, Serli Kiyomi Nakao Ueda, Renata D’Alpino Peixoto   +2 more
doaj   +1 more source