Results 191 to 200 of about 14,325,085 (286)

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

Induction of p53-mediated apoptosis by azacitidine in patient-derived xenograft follicular helper T-cell lymphoma model. [PDF]

Leukemia
Tari Crochet G, Ari-Yuka S, Fischer A, Chour M, Claudel A, Sako N, Robe C, Naudet J, Gonon A, Mboumba DL, Ortonne N, Alcazer V, Delfau-Larue MH, Siebert R, Gaulard P, Lemonnier F.   +15 more
europepmc   +1 more source

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

BAFF promotes follicular helper T cell development and germinal center formation through BR3 signal. [PDF]

JCI Insight
Chen Y, Chen M, Liu Y, Li Q, Xue Y, Liu L, Liang R, Xiong Y, Zhao J, Chen J, Lin W, Wang J, Pan YF, Stohl W, Zheng SG.   +14 more
europepmc   +1 more source

[Dual epigenetic therapy in TET2 gene positive extranodal peripheral T-cell lymphoma with follicular helper T-cell (TFH) phenotype: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2023
Lang JY, Lyu R, Song YY, Zou DH, An G.
europepmc   +1 more source

Abatacept Reduces CD319+ (SLAMF7) Cytotoxic T Cells and Cytokine Production in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by immune dysregulation and fibrosis. We investigated whether abatacept modulates CD319/SLAMF7‐expressing cytotoxic T cells implicated in diffuse cutaneous SSc. Methods In this ancillary ASSET trial analysis, peripheral blood mononuclear cells from 67 participants were analyzed at baseline and months ...
Mikel Gurrea‐Rubio, Laura A. Cooney, Kohei Maeda, Phillip L. Campbell, Qi Wu, Camila I. Amarista, Alexander Stinson, Ray Ohara, Yang Mao‐Draayer, Michael L. Whitfield, Shiv Pillai, Poulami Dey, Johann E. Gudjonsson, Pei‐Suen Tsou, Dinesh Khanna, David A. Fox   +15 more
wiley   +1 more source

Student‐identified barriers to histology learning and the perceived value of coloring as a multimodal educational strategy

Anatomical Sciences Education, EarlyView.
Abstract Histology is a visually complex and cognitively demanding subject often perceived as abstract, memorization‐heavy, and disconnected from clinical practice. Despite its foundational importance, histology is frequently under‐emphasized relative to gross anatomy and lacks interactive, multimodal resources tailored to its unique challenges.
Anika Knowles, Karen Pinder, Tamara A. Franz‐Odendaal   +2 more
wiley   +1 more source

The active form of vitamin D (calcitriol) promotes CXCR5 expression during follicular helper T cell differentiation. [PDF]

Int Immunol
Iwata M, Takada A, Sakamoto R, Song SY, Ito E.   +4 more
europepmc   +1 more source

Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors. [PDF]

J Immunol Res, 2020
Ji LS, Sun XH, Zhang X, Zhou ZH, Yu Z, Zhu XJ, Huang LY, Fang M, Gao YT, Li M, Gao YQ.   +10 more
europepmc   +1 more source

Seeing ourselves in anatomy: Embedding equity, diversity, and inclusivity to transform learning in a UK BSc curriculum

Anatomical Sciences Education, EarlyView.
Abstract Embedding intersectional equity, diversity, and inclusion (EDI) in anatomy education is essential to reflect the growing diversity of student populations, support all learners, and prepare graduates for a more inclusive, socially responsive global workforce.
Michelle Welsh, Ourania Varsou
wiley   +1 more source