Results 141 to 150 of about 13,929,929 (284)

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

The link between circulating follicular helper T cells and autoimmunity. [PDF]

Nat Rev Immunol, 2022
Walker LSK.
europepmc   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Immunological dysregulation of follicular helper T cells, follicular regulatory T cells, and follicular cytotoxic T cells is associated with disease activity and identifies exploratory immune patterns in rheumatoid arthritis

Frontiers in Immunology
BackgroundThe onset and progression of rheumatoid arthritis (RA) are linked to autoantibody production driven by dysregulated germinal center (GC) responses. Follicular helper T cells (Tfh), follicular regulatory T cells (Tfr), and follicular cytotoxic T
Yuxin Fan, Yuxin Fan, Yuxin Fan, Baochen Li, Baochen Li, Baochen Li, Ruihe Wu, Ruihe Wu, Ruihe Wu, Xiaoyang Liu, Xiaoyang Liu, Xiaoyang Liu, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Yuhuan Xie, Yuhuan Xie, Yuhuan Xie, Chong Gao, Caihong Wang, Caihong Wang, Caihong Wang   +21 more
doaj   +1 more source

The Differentiation and Maintenance of SARS-CoV-2-Specific Follicular Helper T Cells. [PDF]

Front Cell Infect Microbiol, 2022
Wang Y, Tian Q, Ye L.
europepmc   +1 more source

Patterns of interspecific variation in labial microarchitecture among anthropoid primates and the evolution of the hominin lips

The Anatomical Record, EarlyView.
Comparative histological and semi‐automated image analysis of primate lips: Masson's trichrome‐stained sagittal sections were segmented to quantify the connective tissue, adipose, and muscular components, enabling interspecific comparisons of labial architecture.
Liat Rotenstreich, Kfir Eliyahu, Nir Edery, Lior Moss, Saleem Eben Bari, Assaf Marom   +5 more
wiley   +1 more source

Synovial Macrophages Expression of OX40L Is Required for Follicular Helper T Cells Differentiation in the Joint Microenvironment. [PDF]

Cells, 2022
Cai X, Zhang M, Ren F, Fei W, Zhang X, Zhao Y, Yao Y, Lin N.   +7 more
europepmc   +1 more source

Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]

, 1998
Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Venaille, T.J., Lee, P.T., Stumbles, P.A., Pimm, C.L., Proksch, S., Holt, P.G., Thomas, J.A.   +6 more
core  

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source