Results 91 to 100 of about 12,893 (183)
Differing Effects of Younger and Older Human Plasma on C2C12 Myocytes in Vitro [PDF]
Ageing is associated with a general reduction of physiological function and a reduction of muscle mass and strength. Endocrine factors such as myostatin, activin A, growth and differentiation factor 11 (GDF-11) and their inhibitory peptides influence ...
Alnaqeeb +42 more
core +2 more sources
The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease [PDF]
The dramatic recent rise in the incidence of allergic or autoimmune inflammatory diseases in the West has been proposed to reflect the lack of appropriate priming of the immune response by infectious agents such as parasitic worms during childhood ...
Al-Riyami +111 more
core +2 more sources
ABSTRACT Background Resistance training (RT) is the first‐line treatment to improve sarcopenia features. However, increasing muscle mass with RT remains challenging and displays inconsistent results. Manipulating training variables may present a novel approach to improve muscle mass gain in sarcopenic individuals. The present study aimed to measure the
Leo Delaire +5 more
wiley +1 more source
High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma [PDF]
Activin A (ActA)/follistatin (FST) signaling has been shown to be deregulated in different tumor types including lung adenocarcinoma (LADC). Here, we report that serum ActA protein levels are significantly elevated in LADC patients (n=64) as compared ...
Alzheimer +58 more
core +1 more source
Neuronal induction and regional identity by co-culture of adherent human embryonic stem cells with chicken notochords and somites [PDF]
The role of somites and notochords in neuroectoderm differentiation from the embryonic ectoderm and its subsequent patterning into regional compartments along rostro-caudal and dorso-ventral axes, especially in humans, remains elusive.
بهاروند, حسين +7 more
core +1 more source
Myocardial infarction (MI) is one of the leading causes of death worldwide, and even though modern medicine has reduced considerably the number of deaths due to MI, patients still undergo serious cardiac issues that dramatically affects their well-being.
José Rodrigues Gomes, Mário Santos
doaj
Structure of Gremlin-1 and analysis of its interaction with BMP-2. [PDF]
Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor-β (TGF-β) signalling family and has a very broad biological role in development.
Hyvönen, Marko +2 more
core +2 more sources
Role of SPARC in Bone Remodeling and Cancer‐Related Bone Metastasis [PDF]
There is a growing socioeconomic recognition that clinical bone diseases such as bone infections, bone tumors and osteoporotic bone loss mainly associated with ageing, are major issues in today0s society.
Brekken, Rolf A. +3 more
core +1 more source
Proteomics of left ventricular structure in the Multi‐Ethnic Study of Atherosclerosis
Aims Proteomic profiling offers an expansive approach to biomarker discovery and mechanistic hypothesis generation for LV remodelling, a critical component of heart failure (HF).
Tess E. Peterson +19 more
doaj +1 more source
Paradigm Shifts In Neural Induction [PDF]
The molecularization of developmental biology was originally seen as a challenge to the integrity of that discipline. However, important new insights from the analysis of gene expression soon transformed the field from one of experimental anatomy to one ...
Gilbert, Scott F.
core +2 more sources

