Results 101 to 110 of about 12,023,937 (197)

Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy

, 2015
Follistatin is an inhibitor of TGF-β superfamily ligands that repress skeletal muscle growth and promote muscle wasting. Accordingly, follistatin has emerged as a potential therapeutic to ameliorate the deleterious effects of muscle atrophy.
A Hagg (13448925), Severine Lamon (13095072), PV Sepulveda (14471580), H Qian (13418208), P Gregorevic (10669521), Clinton Bruce (13064589), RE Thomson (14471448), CE Winbanks (10669509), Aaron Russell (13059132)   +8 more
core  

Follistatin-Related Protein 1 [PDF]

, 2020
openaire   +1 more source

Advance in the study of inhibin, activin and follistatin production in pregnant women

, 1998
This review summarizes the new information on the studies of inhibin, activin, and follistatin production in the placenta during human pregnancy. Inhibin and activin exert suppressive and stimulatory effects, respectively, on the release of FSH in the ...
Qu, Jianping, Thomas, Karl, Jianping Qu, Karl Thomas   +3 more
core   +1 more source

Follistatin-Related Protein 3 [PDF]

, 2020
openaire   +1 more source

Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis

, 2011
Myostatin, a member of the transforming growth factor (TGF)-β superfamily, plays a potent inhibitory role in regulating skeletal muscle mass. Inhibition of myostatin by gene disruption, transgenic (Tg) expression of myostatin propeptide, or injection of ...
Masahiro Kokubo, Kunihiro Tsuchida, Yutaka Ohsawa, Masashi Nakatani, Yoshihide Sunada   +4 more
core   +1 more source

The structure of FSTL3.activin A complex: Differential binding of N-terminal domains influences follistatin-type antagonist specificity

, 2008
Transforming growth factor beta family ligands are neutralized by a number of structurally divergent antagonists. Follistatin-type antagonists, which include splice variants of follistatin (FS288 and FS315) and follistatin-like 3 (FSTL3), have high ...
Schneyer, Alan
core   +1 more source

Low cutaneous follistatin expression is associated with striae gravidarum: A pilot study of the TGF-β/BMP signaling pathway. [PDF]

Biochem Biophys Rep
Tian T, Wang H, Li Y.
europepmc   +1 more source

Grip strength as a systems biomarker of aging: neuromuscular junction constraints and biomarker decoupling in gene therapy. [PDF]

Front Aging
Sewell PE, Jensen C.
europepmc   +1 more source

Secreted Frizzled-Related Protein 2 (SFRP2) Induces Follistatin-Like 1 (FSTL1) to Regulate Dihydrotestosterone (DHT)-Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence. [PDF]

Aging Cell
Huang Y, Bian Q, Shen Y, Ding X, Teng Y, Xu D, Yang X, Fan Y.   +7 more
europepmc   +1 more source

Alterations in systemic and skeletal muscle myostatin regulation are most prominent at disease onset and associate with muscle-related outcomes in idiopathic inflammatory myopathies. [PDF]

Arthritis Res Ther
Vernerová L, Lážnovská L, Baloun J, Balounová V, Vokurková M, Klein M, Verner Z, Kičura T, Mann H, Oreská S, Svobodová K, Kropáčková T, Tomčík M, Ukropec J, Ukropcová B, Vencovský J.   +15 more
europepmc   +1 more source