Results 121 to 130 of about 6,859 (161)

Human placenta and fetal membranes express follistatin-related gene mRNA and protein

Journal of Endocrinological Investigation, 2003
Activin A is a placental glycoprotein and possible biological actions during pregnancy, suggested by experimental data, are the modulation of cytotrophoblast differentiation, placental hormonogenesis and uterotonins secretion. Follistatin-related gene (FLRG) is a 70 amino acids protein which binds activin A with high affinity, and which modulates its ...
P. Ciarmela, P. Florio, P. Toti, FRANCHINI, Antonella, V. Maguer Satta, C. Ginanneschi, OTTAVIANI, Enzo, F. Petraglia   +7 more
openaire   +5 more sources

Follistatin-related protein 1 in asthma: miR-200b-3p interactions affect airway remodeling and inflammation phenotype

International Immunopharmacology, 2022
Follistatin-related protein 1 (FSTL1) is significantly associated with the asthma severity and outcome in humans and diverse mouse models of asthma. Previous studies have also suggested that FSTL1 could activate autophagy and NLRP3, thus playing as a causative agent in the asthma progression.
Fen, Liu, Jintao, Zhang, Dong, Zhang, Qian, Qi, Wenjing, Cui, Yun, Pan, Xiaofei, Liu, Jiawei, Xu, Xinrui, Qiao, Zihan, Wang, Liang, Dong   +10 more
openaire   +2 more sources

Characterization and expression of the follistatin-related protein gene in golden pompano Trachinotus ovatus larvae

Gene Reports, 2020
Abstract The follistatin-related protein (FRSP) gene performs numerous functions through binding with cell regulatory proteins in transforming growth factor beta (TGF-β) superfamily such as activin and myostatin. The FRSP gene has been extensively studied in human and other vertebrate models such as chick and mouse to explore its role for disease ...
Md Mahbubul Hassan, Mingjun Fu, Jian G. Qin, Zhenhua Ma   +3 more
openaire   +1 more source

Difference in sensory dependence of occ1/Follistatin-related protein expression between macaques and mice

Journal of Chemical Neuroanatomy, 2008
occ1/Follistatin-related protein (Frp) is strongly expressed in the primary visual cortex (V1) of macaque monkeys, and its expression is strongly down-regulated by intraocular tetrodotoxin (TTX) injection. The pronounced area selectivity of occ1/Frp mRNA expression occurs in macaques and marmosets, but not in mice, rabbits and ferrets, suggesting that ...
Toru, Takahata, Tsutomu, Hashikawa, Noriyuki, Higo, Shiro, Tochitani, Tetsuo, Yamamori   +4 more
openaire   +2 more sources

Overproduction of the follistatin‐related gene protein in the placenta and maternal serum of women with pre‐eclampsia

BJOG: An International Journal of Obstetrics & Gynaecology, 2007
Objective  To characterise the follistatin‐related gene (FLRG) in pre‐eclampsia, one of the differentially expressed genes in pre‐eclamptic placenta.Design and methods  We examined and compared the messenger RNA (mRNA) and protein levels of FLRG in placentas and maternal sera from women with uncomplicated pregnancy, and those with pre‐eclampsia using ...
K, Pryor-Koishi, H, Nishizawa, T, Kato, H, Kogo, T, Murakami, K, Tsuchida, H, Kurahashi, Y, Udagawa   +7 more
openaire   +2 more sources

Follistatin-related protein 1 interacting partner of Syndecan-1 promotes an aggressive phenotype on Oral Squamous cell carcinoma (OSCC) models

Journal of Proteomics, 2022
Syndecans belong to the family of transmembrane heparan sulfate proteoglycans and are associated with many physiopathological processes, including oral cancer. As previously shown soluble syndecan-1 (SDC1) fragments and synthetic SDC1 peptide were able to induce cell migration in oral cancer cell lines.
Flávia S, Zandonadi, Sami, Yokoo, Daniela Campos, Granato, César, Rivera, Carolina Carneiro Soares, Macedo, Ciro Dantas, Soares, Carolina Moretto, Carnielli, Romênia Ramos, Domingues, Bianca A, Pauletti, Sílvio Roberto, Consonni, Ricardo D, Colleta, Adriana F, Paes Leme   +11 more
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[Pathophysiological functions of follistatin related protein].

Sheng li ke xue jin zhan [Progress in physiology], 2012
Follistatin related protein (FRP) is an extra-cellular glycoprotein, involved in several pathological and physiological processes such as cell proliferation, migration, tissue remodeling, embryonic development, and cell-cell interaction. Nowadays researches showed that FRP possesses dual functions, including inhibiting cell apoptosis and inhibiting ...
Hua, Shen, Yu-Yang, Liu
openaire   +1 more source

Identification of a follistatin-related protein from the tick Haemaphysalis longicornis and its effect on tick oviposition

Gene, 2006
The identification of ovary-associated molecules will lead to a better understanding of the physiology of tick reproduction and vector-pathogen interactions. A gene encoding a follistatin-related protein (FRP) was obtained by random sequencing from the ovary cDNA library of the tick Haemaphysalis longicornis.
Jinlin, Zhou, Min, Liao, Takeshi, Hatta, Miho, Tanaka, Xuenan, Xuan, Kozo, Fujisaki   +5 more
openaire   +2 more sources

cDNA Cloning and Distribution of theXenopusFollistatin-Related Protein

Biochemical and Biophysical Research Communications, 1999
Recently, several proteins which have a follistatin module have been isolated. One of them, the follistatin-related protein (FRP), is encoded by TSC-36 (TGF-beta-stimulated clone 36) in mouse, originally isolated as a cDNA clone up-regulated by TGF-beta1 in mouse osteogenic MC3T3E1 cells.
K, Okabayashi, H, Shoji, Y, Onuma, T, Nakamura, K, Nose, H, Sugino, M, Asashima   +6 more
openaire   +2 more sources

Identification and Characterization of Follistatin-Related Protein-1 Involved in the Regulation of Chinese Perch Skeletal Muscle Hyperplasia

Current Molecular Medicine, 2016
Follistatin-related protein (FSRP), which belongs to a member of the follistatin family, has been postulated to be a new negative regulator of myostatin (MSTN) and is involved in muscle development. In this study, we cloned the complete cDNA sequence of FSRP-1 from Chinese perch muscle.
W, Chu, J, Cheng, X, Zhu, P, Wu, L, Chen, J, Wang, Y, Wu, M, Zeng, J, Zhang   +8 more
openaire   +2 more sources