Results 61 to 70 of about 13,850 (204)

Intraperitoneal administration of follistatin promotes adipocyte browning in high-fat diet-induced obese mice.

PLoS ONE, 2019
With rapid economic development, the prevalence of obesity has increased remarkably worldwide. Obesity can induce a variety of metabolic diseases, such as atherosclerosis, diabetes, hypertension and coronary heart disease, which significantly endanger ...
Haoyu Li, Chuanhai Zhang, Junyu Liu, Wenya Xie, Wentao Xu, Fei Liang, Kunlun Huang, Xiaoyun He   +7 more
doaj   +1 more source

Activin/Follistatin and Atherosclerosis-A Review-

Journal of Atherosclerosis and Thrombosis, 1998
Activin-A, a member of the TGF-beta superfamily, has a variety of important biological functions. Concerning Møs, we demonstrated that MSR which has a key role in disposing of modified LDL is downregulated by activin-A. This leads to a decrease in binding, cell association, and degradation of Ac-LDL, resulting in the inhibition of foam cell formation ...
Kozaki, Koichi, Ouchi, Yasuyoshi
openaire   +3 more sources

Follistatin-respiratory connection predicting all-cause mortality among community-dwelling middle-to-old age individuals: Results from the I-Lan Longitudinal Study

The Journal of Nutrition, Health and Aging
Objectives: The link between aging and pulmonary function decline is well-established, but the underlying mechanisms have yet to be fully revealed. Serum follistatin, a myokine implicated in muscle degeneration, may play a role in age-related pulmonary ...
Hsiao-Chin Shen, Wei-Ju Lee, Chuan-Yen Sun, Wen-Kuang Yu, Wei-Chih Chen, Fei-Yuan Hsiao, Kuang-Yao Yang, Liang-Kung Chen   +7 more
doaj   +1 more source

The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts

Arthritis Research & Therapy, 2019
Background Activin A and follistatin exhibit immunomodulatory functions, thus affecting autoinflammatory processes as found in rheumatoid arthritis (RA).
Magnus Diller, Klaus Frommer, Berno Dankbar, Ingo Tarner, Marie-Lisa Hülser, Lali Tsiklauri, Rebecca Hasseli, Michael Sauerbier, Thomas Pap, Stefan Rehart, Ulf Müller-Ladner, Elena Neumann   +11 more
doaj   +1 more source

Follistatin and the Breast Implant Capsule

Plastic and Reconstructive Surgery - Global Open, 2017
Background: Breast capsular contracture remains an elusive problem faced by plastic surgeons and is the leading long-term complication after breast implantation. Follistatin (Fst) is a protein with known anti-inflammatory and antifibrotic properties and has the potential to limit the severity of diseases associated with ...
Frenkiel, Brett A., Temple-Smith, Peter, de Kretser, David, Southwick, Graeme J.   +3 more
openaire   +2 more sources

Follistatin alters myostatin gene expression in C2C12 muscle cells

, 2004
The objective of the present study was to determine the effects of follistatin addition on myostatin and follistatin gene expression patterns in C2C12 muscle cells.
M. Nazlı, Kocams¸, H., H. Kocams¸, N. Gulmez, Aslan, S., S. Aslan, Gulmez, N., Nazlı, M.   +7 more
core   +1 more source

FSTL3 (follistatin-like 3 (secreted glycoprotein)) [PDF]

, 2013
Review on FSTL3 (follistatin-like 3 (secreted glycoprotein)), with data on DNA, on the protein encoded, and where the gene is ...
Grusch, M
core   +1 more source

Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Skeletal Muscle, 2018
Background Myostatin antagonists are being developed as therapies for Duchenne muscular dystrophy due to their strong hypertrophic effects on skeletal muscle.
Andrea Iskenderian, Nan Liu, Qingwei Deng, Yan Huang, Chuan Shen, Kathleen Palmieri, Robert Crooker, Dianna Lundberg, Niksa Kastrapeli, Brian Pescatore, Alla Romashko, John Dumas, Robert Comeau, Angela Norton, Jing Pan, Haojing Rong, Katayoun Derakhchan, David E. Ehmann   +17 more
doaj   +1 more source

Pegylated Interferon-α Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat

Mediators of Inflammation, 2015
Aims. To measure the expression of activin βA-subunit, activin IIA and IIB receptors, Smad4, Smad7, and follistatin in the liver and the liver and serum concentrations of mature activin-A and follistatin in normal rat following treatment with pegylated ...
Bassem Refaat, Adel Galal El-Shemi, Ahmed Mohamed Ashshi, Elaf Wael Mahamid, Noha Mohammed Al-Qadi   +4 more
doaj   +1 more source

Follistatin as an Inhibitor of Experimental Metastasis [PDF]

Clinical Cancer Research, 2008
Activin, a member of the transforming growth factor-β (TGF-β) superfamily, and its antagonist, follistatin, can regulate cell proliferation, differentiation, angiogenesis, apoptosis, and potentially tumor growth.
openaire   +2 more sources