Results 81 to 90 of about 19,954 (207)
Obesity, Volume 34, Issue 2, Page 382-393, February 2026.ABSTRACT Objective In this study, we investigated the effects of a stem cell‐derived secretome product on adiposity and tissue quality and insulin and glucose levels in obese mice and those undergoing dietary weight loss. Methods Following 16 weeks of high fat diet mice received acute (4 weeks) biweekly intramuscular injections with vehicle or ...
Zachary J. Fennel +11 more
wiley +1 more source
Frontiers in Immunology, 2020 Ascending bacterial pyelonephritis, a form of urinary tract infection (UTI) that can result in hospitalization, sepsis, and other complications, occurs in ~250,000 US patients annually; uropathogenic Escherichia coli (UPEC) cause a large majority of ...
Teri N. Hreha +7 more
doaj +1 more source
Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system [PDF]
, 2014 Follistatin‐like 5 (Fstl5), a member of the follistatin family of genes, encodes a secretory glycoprotein. Previous studies revealed that other members of this family including Fstl1 and Fstl3 play an essential role in development, homeostasis, and ...
Masuda Tomoyuki +7 more
core +2 more sources
Aging Cell, Volume 25, Issue 2, February 2026.This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy +10 more
wiley +1 more source
Frontiers in EndocrinologyIntroductionFollistatin is a secreted protein whose main role is antagonizing the activity of transforming growth factor β (TGF-β) superfamily members.
Conghui Liu +3 more
doaj +1 more source
Neuronal induction and regional identity by co-culture of adherent human embryonic stem cells with chicken notochords and somites [PDF]
The role of somites and notochords in neuroectoderm differentiation from the embryonic ectoderm and its subsequent patterning into regional compartments along rostro-caudal and dorso-ventral axes, especially in humans, remains elusive.
بهاروند, حسين +7 more
core +1 more source
Lifelong exercise, but not short-term high-intensity interval training, increases GDF11, a marker of successful aging: a preliminary investigation [PDF]
, 2017 Lifelong exercise is associated with regulation of skeletal mass and function, reductions in frailty, and successful aging. Yet, the influence of exercise on myostatin and myostatin-interacting factors is relatively under examined in older males ...
Amthor +41 more
core +3 more sources
Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.Non‐invasive biomarkers are needed to further personalize EGFR tyrosine kinase inhibitor (EGFR TKI) osimertinib treatment in non‐small cell lung cancer (NSCLC) patients. By analysing the proteome of extracellular vesicles (EVs) isolated from an osimertinib resistant NSCLC cell line and from serum of patients given osimertinib in second line within the ...
Albano Cáceres‐Verschae +15 more
wiley +1 more source
TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]
, 2019 OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core +2 more sources
Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal +10 more
wiley +1 more source