Results 81 to 90 of about 19,656 (205)

Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle [PDF]

open access: yes, 2014
peer-reviewedBackground In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination.
Diskin, Michael G.   +5 more
core   +1 more source

Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang   +7 more
wiley   +1 more source

Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring

open access: yesFrontiers in Immunology, 2020
Ascending bacterial pyelonephritis, a form of urinary tract infection (UTI) that can result in hospitalization, sepsis, and other complications, occurs in ~250,000 US patients annually; uropathogenic Escherichia coli (UPEC) cause a large majority of ...
Teri N. Hreha   +7 more
doaj   +1 more source

Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins [PDF]

open access: yes, 2005
© The Company of Biologists Ltd 2005Paracrine factors secreted by the oocyte regulate a broad range of cumulus cell functions. Characteristically, cumulus cells have a low incidence of apoptosis and we proposed that this is due to oocyte-secreted factors
Amato, F.   +4 more
core   +2 more sources

Helicobacter pylori, Inflammation, and Long‐Term Outcome in Patients With Acute Myocardial Infarction: A Prospective Cohort Study

open access: yesHelicobacter, Volume 31, Issue 2, March/April 2026.
ABSTRACT Background Helicobacter pylori (Hp) and its virulence factor Cytotoxin‐associated gene A (CagA) have been linked to myocardial infarction (MI), but the mechanisms are unknown. This study aims to test if Hp infection and CagA are associated with pre‐specified inflammatory and vascular biomarkers in patients with MI and to explore whether a ...
Martin O. Sundqvist   +12 more
wiley   +1 more source

Different types of exercise and myocardial angiogenesis regulation: A scoping review of cardiac‐specific evidence in animal models

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Abstract Exercise promotes myocardial angiogenesis, yet molecular responses vary by modality, and cardiac‐specific evidence in healthy models remains fragmented. This study aimed to map biomolecular regulators of myocardial/coronary angiogenesis across exercise types in healthy animal models. PRISMA‐ScR scoping review.
Putri Karisa   +5 more
wiley   +1 more source

Activin/TGFβ and BMP crosstalk determines digit chondrogenesis [PDF]

open access: yes, 2008
The progress zone (PZ) is a specialized area at the distal margin of the developing limb where mesodermal cells are kept in proliferation and undifferentiated, allowing limb outgrowth.
1000010205429   +5 more
core   +11 more sources

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu   +12 more
wiley   +1 more source

Functional role of AKT signaling in bovine early embryonic development: potential link to embryotrophic actions of follistatin

open access: yesReproductive Biology and Endocrinology, 2018
Background TGF-β signaling pathways regulate several crucial processes in female reproduction. AKT is a non-SMAD signaling pathway regulated by TGF-β ligands essential for oocyte maturation and early embryonic development in the mouse, but its regulatory
Mohamed Ashry   +7 more
doaj   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

open access: yesAdvanced Science, Volume 13, Issue 10, 18 February 2026.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang   +9 more
wiley   +1 more source

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