Results 41 to 50 of about 376,405 (258)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Insights into German Consumers’ Perceptions of Virtual Fencing in Grassland-Based Beef and Dairy Systems: Recommendations for Communication

Animals, 2020
The share of cattle grazing on grassland is decreasing in many European countries. While the production costs of intensive stall-based beef and dairy systems are usually lower per kg product, grazing-based systems provide more ecosystem services that are
Ekaterina Stampa, Katrin Zander, Ulrich Hamm   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Data covering soil management practices and farm characteristics on Swiss arable farms

Scientific Data
Soil health is the cornerstone of sustainable agriculture, but studies have shown that agricultural soils are degrading due to inadequate soil management practice adoption. To understand the status quo, we surveyed 2,728 Swiss arable farms in 2024.
Charles Rees, Lorin Ineichen, Robert Finger, Christian Grovermann   +3 more
doaj   +1 more source

The Food and Agriculture Organization food-composition initiative [PDF]

The American Journal of Clinical Nutrition, 1997
The 1992 International Conference on Nutrition, new legislation in developing countries, and international trade agreements have renewed interest in food-composition data. Because of the costs involved in gathering such information and the need for it to be uniform, collaborative efforts are required. The production of new food-composition data must be
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Spent brewer's yeast extracts as a new component of functional food

Czech Journal of Food Sciences, 2016
The use of yeast extracts as a natural and valuable additive ingredient intended for the production of functional food and dietary supplements were demonstrated.
Bartłomiej Podpora, Franciszek Świderski, Anna Sadowska, Rita Rakowska, Grażyna Wasiak-Zys   +4 more
doaj   +1 more source

Organic Food Awareness in Turkey

Emirates Journal of Food and Agriculture, 2015
Abstract The objective of this study was to determine which variables may affect consumers’ knowledge and awareness about organic foods in Turkey. The data was collected from 786 consumers who live in urban areas and it was analyzed by means of multinomial logistic regression model. The level of consumer awareness is calculated as 38%.
Demirtas, Bekir, Parlakay, Oguz, Tapki, Nuran   +2 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source