Results 231 to 240 of about 476,073 (321)

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

open access: yesAngewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson   +5 more
wiley   +2 more sources

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics

open access: yesAngewandte Chemie, EarlyView.
This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang   +9 more
wiley   +2 more sources

Food-Borne Parasitic Diseases

open access: yesJournal of the Korean Medical Association, 2007
openaire   +1 more source

Climate justice as a public health imperative: a perspective from Sierra Leone considering the 2025 International Court of Justice opinion. [PDF]

open access: yesInfect Dis Poverty
Kamara IF   +9 more
europepmc   +1 more source

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