Results 71 to 80 of about 3,503,938 (259)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Refined exposure assessment of ethyl lauroyl arginate based on revised proposed uses as a food additive [PDF]

, 2013
Following a request from the European Commission, the European Food Safety Authority (EFSA) carried out a refined exposure assessment of ethyl lauroyl arginate (LAE) from its use as a food additive, for children and adults, based on revised proposed uses.
European Food Safety Authority
core   +1 more source

Examination of the Use of Bacteriophage as an Additive and Determining Its Best Application Method to Control Listeria monocytogenes in a Cooked-Meat Model System

Frontiers in Microbiology, 2020
The study examined the efficacy of using bacteriophage as an additive in a cooked-meat model system to control growth of contaminating Listeria monocytogenes during subsequent storage.
Hanie Ahmadi, Hanie Ahmadi, Shai Barbut, Loong-Tak Lim, S. Balamurugan   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Follow-up of the re-evaluation of silver (E 174) as a food additive (EFSA-Q-2023-00169). [PDF]

EFSA J
Silver (E 174) is a food colour that was re‐evaluated by the EFSA ANS Panel (2016). The ANS Panel concluded that the information available then, was insufficient to assess the safety of silver as food additive.
EFSA Panel on Food Additives and Flavourings (FAF), Andreassen M, Aquilina G, Bastos ML, Boon P, Castle L, Fallico B, FitzGerald R, Frutos Fernandez MJ, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Kurek MA, Louro H, Morales P, Passamonti S, Oomen A, Corsini E, Wright M, Furst P, Gaffet E, Loeschner K, Mast J, Undas A, Mech A, Rincon AM, Ruggeri L, Smeraldi C.   +27 more
europepmc   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Potencies Of Natural Food Additives As Bioactive Ingredients

, 2002
Food additive is one of the most important ingredients in any food products. It may improve food preference (sensory quality) of a product, extend a product's shelf life, facilitate food processing, and improve health benefits of a product.
Wijaya, C. Hanny
core  

additive: Bindings for Additive TidyModels

, 2022
Fit Generalized Additive Models (GAM) using 'mgcv' with 'parsnip'/'tidymodels' via 'additive' . 'tidymodels' is a collection of packages for machine learning; see Kuhn and Wickham (2020) ). The technical details of 'mgcv' are described in Wood (2017) .To
Badr, Hamada S.
core   +1 more source