Results 161 to 170 of about 3,449,307 (399)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Effect of Preheating Treatment before Defatting on the Flavor Quality of Skim Milk

open access: yesMolecules, 2019
Skim milk has a poor flavor due to the lack of fat. Finding ways to improve the flavor quality of skim milk has attracted the attention of more and more researchers.
Lingjun Tong   +6 more
doaj   +1 more source

Risk perception of food additives in Hungary [PDF]

open access: yes, 2010
On the basis of international surveys, Hungarian consumers stated serious aversion against food additives. The aim of our work was to get more detailed information about Hungarian consumers' risk perception with special regard to food additives. For this
Bánáti, Diána, Szűcs, Viktória
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Phycocyanin diminishes the viability of non-small cell lung cancer cells via induction of autophagy

open access: yesJournal of Functional Foods, 2022
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer mortality worldwide. Phycocyanin, a type of marine food additives, has been reported to exert antineoplastic effects in NSCLC.
Shuai Hao   +6 more
doaj  

Feed additives : annual report 2009 of the National Reference Laboratory [PDF]

open access: yes, 2010
This report of the National Reference Laboratory (NRL) for feed additives describes the activties employed in 2010. The main tasks of the NRL are: giving assistance to the European Union Reference Laboratort (EU-RL) on their request and advice and ...
Beek, W.M.J.   +2 more
core   +4 more sources

Plant volatiles: Using Scented molecules as food additives

open access: yesTrends in Food Science & Technology, 2022
N. Derbassi   +5 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Highly Efficient Enrichment of Heterocyclic Aromatic Amines in Meat Products Using the Magnetic Metal—Organic Framework Fe3O4@MOF-545-AMSA

open access: yesMolecules
Heterocyclic aromatic amines (HAAs), known for their mutagenic and carcinogenic potential, are formed during the heating of protein-rich food items.
Yang Wang   +3 more
doaj   +1 more source

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